In PNAS this week: effects of gene deletions on bacterial metabolic networks, genetic responses to sea star wasting disease, and more.
Both a genome-wide association study and a rare variant burden analysis homed in on a role for KIF5A mutations in amyotrophic lateral sclerosis.
In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.
The consortium aims to identify tuberculosis protein targets and corresponding small molecule inhibitors that can be used to develop drugs to shorten therapy duration.
The team aims to release the new resource sometime next year, with the hope that it will become as widely used as other institute databases.
In Cell this week: host-microbe interactions and cancer drug response; links between transcription rate, mRNA translation, and methylation; and more.
The funding will, in part, support efforts to expand the project's catalog of functional elements and understand their roles in different contexts.
The Ebola virus may have mutated to better infect humans during the 2014 outbreak, the New York Times reports.
The healthcare provider organizations are tasked with managing patient enrollment in the Precision Medicine Initiative.
Tufts scientists and their colleagues called for steps to ensure that disadvantaged groups benefit from genetically based diagnoses and treatments.
The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.
The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.
New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.
In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.