UMass Dog Breeds Explain Only Small Part of Behavior, New Genetic Analysis Finds Many behavioral traits among dogs appear to be heritable, but the study did not find any that were breed-specific. Research Groups Modify Gene Editing Tools to Improve Efficiency, Delivery One study presents an approach to improve the efficiency of base editing of mitochondrial DNA, while the other describes a split prime editor for ease of delivery. Single-Cell Sequencing Uncovers Signaling Pathways Involved in Skin Discoloration Disorder The analysis also suggested that unaffected skin from individuals with vitiligo may be in a subclinical inflammatory state. BioFire Diagnostics, UMass Medical Coronavirus Tests Get FDA Emergency Use Authorization BioFire's test is designed to detect and differentiate between SARS-CoV-2 and other respiratory pathogens, while UMass Medical's test is only for SARS-CoV-2. GWAS Meta-Analysis of East Asian Individuals Link 60 New Loci to Diabetes Risk The researchers said the findings underscore the need to study disease variants in a range of ancestral backgrounds. Dec 10, 2018 Germline Genome Editing Experiment's Scientific Uncertainty Draws Ire of CRISPR Experts Premium Aug 31, 2018 NSF Awards $10M in EDGE Program Grants Mar 21, 2018 Loss-of-Function KIF5A Mutations Linked to Amyotrophic Lateral Sclerosis Oct 31, 2017 DoD Awards $10M to Consortium to ID New TB Drug Targets Aug 31, 2017 EBI Team Developing Genome Editing Resource for CRISPR Experimental Data Premium Feb 3, 2017 NHGRI Commits $31.5M to Expand ENCODE Project Oct 13, 2016 NIH Adds Four Medical Center Groups to Precision Medicine Initiative Cohort Program Aug 9, 2016 Policy Changes Needed to Prevent Disparities in Genetically Based Medicine Jul 25, 2016 Novel ALS Susceptibility Variants Uncovered in Pair of Studies Mar 17, 2016 Team IDs Potential Gut Microbe Marker for Necrotizing Enterocolitis in Infants Jan 11, 2016 PAG Presentation Describes Dog Model for OCD; Crowdsourcing Study of Dog Behavior Genetics Oct 28, 2015 UMass Scientists Lead Effort to Excise Latent HIV With CRISPR/Cas9 Premium Sep 29, 2015 Court Rules Against University of Utah in RNAi IP Inventor Dispute Mar 24, 2015 Scientists Track Chromosomes with Multicolor GFP-tagged CRISPR/Cas9 Premium Feb 4, 2015 UMass-led Team Exploring Dendritic Cells as Model for Gene Expression Research Premium Jan 5, 2015 NHGRI Awards $28.3M to Uncover Secrets of Gene Regulation Oct 1, 2014 Population Study Prompts New View of Monarch Butterfly Migratory History Sep 26, 2014 NSF Awards $1.9M for Interdisciplinary Study of Bat Senses, Evolution Sep 4, 2014 Court Dismisses Suit over Inventorship of Seminal RNAi Patents Premium Aug 21, 2014 Genomics in the Journals Aug 21, 2014 Load More Breaking News Bio-Rad Laboratories, Cytek Biosciences Partner on Flow Cytometry Reagents Tecan Inks Deals for NGS Library Prep System With Element Biosciences, Singular Genomics Genomenon, Flagship Biosciences Partner on Biomarker Discovery, Companion Dx Development Velsera to Integrate Arima Genomics Gene Fusion Test in Pierian Clinical Platform Evonetix Raises $24M in Extended Series B Funding Round The Scan Study Points to Tuberculosis Protection by Gaucher Disease Mutation A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds. SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource. Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages. UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.