Both a genome-wide association study and a rare variant burden analysis homed in on a role for KIF5A mutations in amyotrophic lateral sclerosis.
In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.
The consortium aims to identify tuberculosis protein targets and corresponding small molecule inhibitors that can be used to develop drugs to shorten therapy duration.
The team aims to release the new resource sometime next year, with the hope that it will become as widely used as other institute databases.
In Cell this week: host-microbe interactions and cancer drug response; links between transcription rate, mRNA translation, and methylation; and more.
The funding will, in part, support efforts to expand the project's catalog of functional elements and understand their roles in different contexts.
The Ebola virus may have mutated to better infect humans during the 2014 outbreak, the New York Times reports.
The healthcare provider organizations are tasked with managing patient enrollment in the Precision Medicine Initiative.
Tufts scientists and their colleagues called for steps to ensure that disadvantaged groups benefit from genetically based diagnoses and treatments.
The researchers particularly highlighted C21orf2 and NEK1, which are involved in cilial and mitochondrial function.
A draft bill released by the US House of Representatives appropriations committee would increase the 2019 National Institutes of Health budget by 3 percent.
Bloomberg looks into privacy issues raised by law enforcement's use of genetic genealogy sites.
NBC News reports on the Earth BioGenome Project, which aims to sequence all eukaryotic life on Earth.
In Science this week: environmental DNA can help in studies of marine animals, and more.