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Dog Breeds Explain Only Small Part of Behavior, New Genetic Analysis Finds

Many behavioral traits among dogs appear to be heritable, but the study did not find any that were breed-specific.

Research Groups Modify Gene Editing Tools to Improve Efficiency, Delivery

One study presents an approach to improve the efficiency of base editing of mitochondrial DNA, while the other describes a split prime editor for ease of delivery.

Single-Cell Sequencing Uncovers Signaling Pathways Involved in Skin Discoloration Disorder

The analysis also suggested that unaffected skin from individuals with vitiligo may be in a subclinical inflammatory state.

BioFire Diagnostics, UMass Medical Coronavirus Tests Get FDA Emergency Use Authorization

BioFire's test is designed to detect and differentiate between SARS-CoV-2 and other respiratory pathogens, while UMass Medical's test is only for SARS-CoV-2.

GWAS Meta-Analysis of East Asian Individuals Link 60 New Loci to Diabetes Risk

The researchers said the findings underscore the need to study disease variants in a range of ancestral backgrounds.

Dec 10, 2018

Germline Genome Editing Experiment's Scientific Uncertainty Draws Ire of CRISPR Experts
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Aug 31, 2018

NSF Awards $10M in EDGE Program Grants

Mar 21, 2018

Loss-of-Function KIF5A Mutations Linked to Amyotrophic Lateral Sclerosis

Oct 31, 2017

DoD Awards $10M to Consortium to ID New TB Drug Targets

Aug 31, 2017

EBI Team Developing Genome Editing Resource for CRISPR Experimental Data
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Feb 3, 2017

NHGRI Commits $31.5M to Expand ENCODE Project

Oct 13, 2016

NIH Adds Four Medical Center Groups to Precision Medicine Initiative Cohort Program

Aug 9, 2016

Policy Changes Needed to Prevent Disparities in Genetically Based Medicine

Jul 25, 2016

Novel ALS Susceptibility Variants Uncovered in Pair of Studies

Mar 17, 2016

Team IDs Potential Gut Microbe Marker for Necrotizing Enterocolitis in Infants

Jan 11, 2016

PAG Presentation Describes Dog Model for OCD; Crowdsourcing Study of Dog Behavior Genetics

Oct 28, 2015

UMass Scientists Lead Effort to Excise Latent HIV With CRISPR/Cas9
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Sep 29, 2015

Court Rules Against University of Utah in RNAi IP Inventor Dispute

Mar 24, 2015

Scientists Track Chromosomes with Multicolor GFP-tagged CRISPR/Cas9
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Feb 4, 2015

UMass-led Team Exploring Dendritic Cells as Model for Gene Expression Research
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Jan 5, 2015

NHGRI Awards $28.3M to Uncover Secrets of Gene Regulation

Oct 1, 2014

Population Study Prompts New View of Monarch Butterfly Migratory History

Sep 26, 2014

NSF Awards $1.9M for Interdisciplinary Study of Bat Senses, Evolution

Sep 4, 2014

Court Dismisses Suit over Inventorship of Seminal RNAi Patents
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Aug 21, 2014

Genomics in the Journals Aug 21, 2014

Breaking News
The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.