UK Biobank

Researchers were able to classify 1,244 of 4,585 putatively clinically relevant rare variants genotyped on the UKB microarray as high quality.

Researchers uncovered nearly a hundred loci to general risk tolerance and hundreds more to particular risky behaviors.

Researchers documented genetic associations, trait heritability, and more with data from GWAS on 778 binary or non-binary traits in UK Biobank participants.

The phenome-wide association study focused on SNPs near potential drug target sites with ties to one or more phenotypes that might impact target suitability.

The UK Biobank has collected genotyping, medical, and other phenotypic data on nearly 500,000 individuals, which it says will fuel additional studies.

Genes and pathways related to mesenchymal biology, connective tissue, and conditions like obesity came to the forefront when researchers analyzed the new susceptibility loci.