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The US National Institutes of Health is sending tissue chips to space to study physiological changes that astronauts undergo in microgravity.

Prospective research suggests DNA and RNA sequencing can reveal pathogen, microbiome, and host expression features to detect lower respiratory tract infections.

GWAS summary statistics data led to three main loci with ties to both Alzheimer's and cardiovascular disease, with additional enrichment at lipid-related sites.

The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.

Researchers found that combining tumor and cancer cell line data with their MAGNETIC analysis approach could enhance drug response predictions.

Investigators developed a droplet digital PCR assay targeting driver mutations and found that changes in circulating DNA were correlated with response to radiation.

Using the publicly available ImmPort database, researchers standardized and analyzed immune-related data for more than 10,300 healthy individuals.

Researchers explored the role of de novo variants and copy number alterations in the disease using new and existing exome sequences for children with Tourette disorder and their parents.

In Science this week: common metastatic driver genes, inhibitors of CRISPR, and more.

These Cas inhibitors — published in two studies — inhibit the activity of several Type V-A and Type I-C CRISPR systems, including several Cas12a orthologs.

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.