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Scientists using gene editing within a patient to try to treat his inherited metabolic disease, the Associated Press reports.

The researchers found that most advanced EGFR-mutant lung cancer patients harbored changes in an average of two to three other oncogenes.

Two studies led by Cleveland Clinic researchers found that a variant in a gene involved in androgen synthesis can help predict response to different prostate cancer therapies.

The developers said that their multivariant analysis does a better job than using APOE E4 alone at identifying those at greatest risk of developing Alzheimer's. 

This Week in PNAS

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

A pair of studies has established a potential role for specific gut bacteria in the progression of MS, suggesting therapeutic targeting of the microbiota as a potential treatment.

This Week in PNAS

In PNAS this week: links between the gut microbiome and multiple sclerosis, and more.

The researchers used this approach to show how non-coding variation associated with human immune dysfunction alters context-specific gene programs. 

The consortium aims to advance the use of genomics in the clinic, with a particular  focus on diverse and underserved patient populations.

The $10 million donation from Mark Zuckerberg and Priscilla Chan should accelerate data sharing and alleviate shortage in bioinformatics expertise.

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The former commissioner of the FDA has returned to the venture capital firm New Enterprise Associates as a special partner on the healthcare investment team.

Astronauts have edited yeast genes on the International Space Station in an experiment designed to show how cells repair themselves in space.

Emory University has found that two of its researchers failed to divulge they had received funds from China, according to the Atlanta Journal-Constitution.

In Science this week: influence of the nuclear genome on human mitochondrial DNA, and more.