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UCSF

CU Denver and UC San Francisco teams are independently performing whole-genome sequencing to find genes involved in reduced efficacy of a common bronchodilator drug.

Sample Ethics

The authors of and the journal that published the sequencing study of the Atacama skeleton have responded to concerns over how the sample was obtained.

The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.

Mutations identified in DNA from the infant's skeleton were linked to bone disorders, including scoliosis, dwarfism, and skeletal dysplasia.

Fresh Take on Ras

NPR reports on new work to find drugs to target the RAS cancer gene.

Researchers also combined the 121 SNPs they found with pharmacy data to develop a risk score to predict when patients would start lipid-lowering treatments.

The aim of the clinic is to educate and answer patients' questions about their health risks and consumer genetic testing they've ordered online.  

In PNAS this week: DNA damage associated with e-cigarette exposure, inflammasome inhibition by OLT1177, and more.

Will They Renew?

As the California Institute for Regenerative Medicine runs out of funds, NPR asks whether states will again fund stem cell research.

The firm licensed two methods that help enrich for rare sequences in a complex background that it plans to use in cell-free DNA and microbiology tests.

Pages

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.