Researchers uncover anti-CRISPR proteins that could help genetic engineering to be safer.
Derived from Listeria phages, the study found four new proteins that inhibit Cas9 activity, two of which also work in E. coli and engineered human cells.
Researchers at UCSF used CRISPR interference to knockdown lncRNA transcripts, then assayed for cell growth to get the final list of almost 500.
Aviv Regev and Jonathan Weissman have jumped into the single-cell RNA-sequencing, pooled CRISPR screen fray.
The funds will support TGen's efforts to use graphics processing units to reduce single-cell transcriptome data analysis times from months to days.
The projects focus on early treatment of prostate cancer and cataloguing mutations in difficult-to-diagnose diseases, among other things.
When it comes to fully enrolling infants in sequencing studies, parental enthusiasm sometimes seems to wane due to logistical considerations and privacy concerns.
Results from a study using the database showed that patients with high expression of a certain gene signature had better outcomes with radiation therapy than without it.
Researchers have developed a new pipeline to uncover novel transmission patterns in mother-infant microbiomes and marine metagenomes.
The healthcare provider organizations are tasked with managing patient enrollment in the Precision Medicine Initiative.
The New York City Police Department will be removing DNA profiles from a local database if they are from people who were never convicted of a crime, the New York Times reports.
Science reports that accusations of sexual assault against a microbiome researcher has also led to questions about his academic certifications.
Wired reports that researchers are analyzing the DNA fish leave behind in water to study their populations.
In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.