UCSF Single-Cell Genomics Study Elucidates Viral, Host Factors of Human Cytomegalovirus The researchers use pooled CRISPR interference to define the function of each factor involved in the infection of primary human fibroblasts. Metagenomic Infectious Disease Sequencing Test Repurposed for Cancer Detection From CSF Samples Premium The assay from a Stanford and UCSF team allows clinicians to scan for multiple cancers of the central nervous system and to reanalyze past samples. Multi-Ethnic Migraine GWAS Uncovers Risk Loci Specific to Sex, Ancestry Investigators analyzed genetic data for more than half a million individuals, detecting susceptibility sites specific to women or European individuals. CRISPRoff Reversible Epigenome Editing Method Could Enable Safer, More Precise Therapeutics Premium UCSF and MIT researchers have developed a way to edit the epigenome and then completely reverse the changes, when needed. Prostate Cancer Study Shows Oncotype DX GPS Test Accurately Measures Long-Term Outcomes Premium The 20-year study showed the test provided an accurate assessment of the risk of long-term metastases and mortality for patients with localized prostate cancer. Mar 19, 2021 NephroSant Readies Launch of Kidney Transplant Rejection Assay Premium Feb 9, 2021 Germline Genetic Variants May Influence Tumor Immune Microenvironment, Treatment Response Jan 21, 2021 Lung Cancer Metastasis Study Relies on CRISPR-Based Method to Track Single-Cell Lineages Jan 15, 2021 Mammoth Biosciences Taking Lead Role in DARPA-Funded Development of Pathogen Detection Tech Premium Jan 14, 2021 DARPA Awards $36.7M to Six Organizations for Gene Editing-Based Dx, Biosurveillance Tech Dec 21, 2020 COVID Assays Using CRISPR, Smartphones Show Potential for At-Home Testing Premium Dec 4, 2020 Breast Cancer Trial Data Supports Neoadjuvant Use of Natera Liquid Biopsy Premium Nov 9, 2020 Metagenomic Sequencing Can Quickly Identify Pathogens in Body Fluids, New Study Finds Oct 19, 2020 Light-Controlled CRISPR 'Off Switch' Enables Precise Editing, Fewer Off-Target Effects Premium Oct 16, 2020 SARS-CoV-2 Protein Interaction Study Reveals Key Proliferation Pathways, Possible Drug Targets Premium Oct 14, 2020 Epigenomic Study of Brain Development Uncovers Cell Type-Specific Regulatory Programs Oct 7, 2020 Post-mortem Melanocyte Mutations Provide Melanoma Clues Aug 20, 2020 Lung Cancer Therapy Leads to Transcriptional Changes, Single-Cell Study Shows Aug 18, 2020 Ebola Virus Appears to Undergo Distinct Changes in Bat, Human Host Cell Line Experiments Aug 14, 2020 Mission Bio Seeks to Increase Drug Trial Collaborations, Improve Gene and Cell Therapy Efficacy Premium Aug 10, 2020 Newborn Exome Sequencing Shows Potential to Help Find Inborn Errors of Metabolism Jul 29, 2020 Akoya Biosciences, UCSF Launch Predictive Cancer Biomarker Collaboration Jul 13, 2020 Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes Jul 10, 2020 FDA Grants EUA for UCSF, Broad Institute, BioSewoom Coronavirus Tests Jun 23, 2020 Advanced CRISPR Screens Uncover Possible Novel Targets for Cancer Therapies Premium Load More Breaking News In Ongoing False Advertising Suit, Judge Allows Natera Counterclaims Against Guardant Health Centogene Strikes Rare Disease Target Discovery Deal With Insilico Medicine Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution The Scan Transplant Tests Edited Pig Kidneys The Associated Press reports a University of Alabama-Birmingham team transplanted genetically modified pig kidneys into a brain-dead human patient. UK Changes Some Gene-Edited Crop Rules A new law may enable gene-edited crops to be sold in the UK within about five years, New Scientist says. Pill Works Against Omicron in Lab Pfizer's antiviral pill to treat SARS-CoV-2 appears to work against the Omicron variant, the Wall Street Journal reports. Nature Papers Find Genetic Risk Factor for Smell, Taste Loss in COVID-19; Analyze TB Granulomas In Nature this week: genome-wide association study find locus linked to the risk COVID-19 patients losing their sense of taste or smell, and more.