UCSF

Researchers explored the role of de novo variants and copy number alterations in the disease using new and existing exome sequences for children with Tourette disorder and their parents.

This Week in Science

In Science this week: common metastatic driver genes, inhibitors of CRISPR, and more.

These Cas inhibitors — published in two studies — inhibit the activity of several Type V-A and Type I-C CRISPR systems, including several Cas12a orthologs.

The report advises that although sequencing the genomes of infants can be appropriate in some specific cases, we shouldn’t implement large-scale programs to test healthy babies.

Testing with Cepheid's molecular TB assay can shorten the amount of time suspected patients need to be isolated and save thousands of dollars per patient.

This Week in Science

In Science this week: genetic and epidemiological study tracking recent Brazilian yellow fever outbreak, and more.

The firm said it will use the funds to build its IP portfolio, expand its team, and develop an infrastructure for partners to build on its CRISPR platform.

This Week in Cell

In Cell this week: structural variants affecting regulatory loci in prostate cancer, immune features in the breast cancer microenvironment, and more.

A new paper critiques the analysis and conclusions of the Atacama mummy genome sequencing study.

The researchers said their method for mapping genetic interactions can serve as a blueprint for mapping the genetic landscape of human cells.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.