UCSD
Science Papers Present Resource for Integrated Spatial Genomics, Cancer Protein Interactions
In Science this week: resource combines images of genomic loci, as well as RNA and epigenetic data; and more.
Sequencing Study Points to Prenatal Development Syndrome, Possible Treatment Strategy
With the help of sequencing, researchers identified several families affected by Zaki syndrome, caused by potentially targetable mutations affecting Wnt signaling.
The method, which can scan for interactions across a cell's entire proteome, is drawing interest from entities looking to both use and commercialize it.
Clonal Mosaic Variants in Sperm Are Stable Over Time, Play Role in Hereditary Disease Transmission
The variants' patterns and stability over time suggest they likely arose during embryogenesis, according to the researchers.
Large-Scale Depression Genetic Study Uncovers Additional Risk Loci, Ties to Potential Drugs
The analysis drew upon data from the Million Veteran Program and other large-scale efforts and underscores the genetic complexity of depression.