UCSD

There are some deep divisions between the three main databases, some due to competitive pressures and others because of the nature of metabolomics.

Using data for almost 10,900 Latino individuals with diverse ancestry, investigators identified distinct patterns for risky or protective APOE variants.

This Week in Nature

In Nature this week: genome sequences of two giant tortoises, genome assemblies and annotations for two allotetraploid cotton species, and more.

Investigators shared data at an oncology meeting last week, showing that the test has high sensitivity and specificity in a blinded case-control cohort that included early-stage tumors.

The researchers hope the datasets from their study can help to explain the effects of disease-associated variants on specific cell types of the immune system.

This Week in Cell

In Cell this week: epigenetic change linked to glioblastomas, rare and low-frequency variants contributing to multiple sclerosis risk, and more.

The projects are organized by the Eliminate Cancer Initiative, the National Brain Tumor Society, and the Pediatric Brain Tumor Foundation.

New Scientist reports that researchers have tested an ALS gene therapy in a mouse model of disease.

In Genome Research this week: transcriptomic profiles of centenarians, role for PRDM9 expression in various tumor types, and more.

UCSD plans to expand the Metabolomics Workbench to include a wide range of clinical trials data including demographics and trial protocols.

Pages

Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.