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In PLOS this week: method to account for sequencing errors in phylogenies, study of influenza A in Switzerland, and more.

In Nature this week: mammalian genomes give insight into selection, multiple-genome alignment program, and more.

In a PrecisionFDA challenge, DeepVariant calls of PacBio HiFi reads topped 99 percent precision and recall for SNVs and indels, bringing HiFi in line with Illumina. 

Using ultra-long read and other sequence data, researchers came up with a de novo X chromosome assembly that covers parts of the sex chromosome missed in the past.

In Cell this week: strategy for prophylactic antiviral CRISPR in human cells; influence of obesity, genetics, and hormone signaling on pancreatic ductal adenocarcinoma; and more.

An international team of researchers analyzed genome-wide data from 89 individuals to reconstruct the population history of the region.

Chinese researchers conducted a systematic comparison between the newly discovered coronavirus genome and SARS-like viruses that caused previous epidemics.

By looking at genes and pathways with altered expression in tumor samples, researchers uncovered potential treatment targets beyond those provided by tumor DNA testing.

Researchers have sequenced pumas from North and South America to enable better identification of inbreeding, Cosmos magazine reports.

At ASHG, researchers showed why they're moving away from limited, linear human reference genome representations and towards a more inclusive future.

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The Wall Street Journal reports on gaps in COVID-19 testing affecting less affluent urban areas and rural locations.

According to NBC News, new SARS-CoV-2 variants are making it harder for researchers to model the course of the pandemic.

The New York Times reports that experts say President Joe Biden's goal of vaccinating 1 million people a day in the US in the next 100 days is too low a bar.

In Science this week: single-cell lineage tracing technique applied to study lung cancer metastasis, and more.