In a PrecisionFDA challenge, DeepVariant calls of PacBio HiFi reads topped 99 percent precision and recall for SNVs and indels, bringing HiFi in line with Illumina.
Using ultra-long read and other sequence data, researchers came up with a de novo X chromosome assembly that covers parts of the sex chromosome missed in the past.
In Cell this week: strategy for prophylactic antiviral CRISPR in human cells; influence of obesity, genetics, and hormone signaling on pancreatic ductal adenocarcinoma; and more.
Chinese researchers conducted a systematic comparison between the newly discovered coronavirus genome and SARS-like viruses that caused previous epidemics.
By looking at genes and pathways with altered expression in tumor samples, researchers uncovered potential treatment targets beyond those provided by tumor DNA testing.
The anonymous gift, to be made in annual installments over 10 years, will support interdisciplinary work at the campus's Genomics Institute headquarters.
