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In Science this week: common metastatic driver genes, inhibitors of CRISPR, and more.

These Cas inhibitors — published in two studies — inhibit the activity of several Type V-A and Type I-C CRISPR systems, including several Cas12a orthologs.

The firm said it will use the funds to build its IP portfolio, expand its team, and develop an infrastructure for partners to build on its CRISPR platform.

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.

In Nature this week: novel soil-dwelling bacteria may be source of molecules with biomedical potential, and more.

Three CRISPR researchers are to receive the Kavli Prize in nanoscience, according to the Associated Press.

Inder Verma had been on leave from PNAS since December after three female scientists at the Salk Institute filed a lawsuit claiming gender discrimination.

Split?

Reuters reports that the panel hearing the CRISPR gene editing patent case appears split.

The company said it plans to develop a CRISPR-enabled platform capable of detecting any biomarker or disease containing DNA or RNA.

Diving Evolution

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

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Politico notes that the Biden Administration has not yet nominated a permanent Food and Drug Administration commissioner. 

Anthony Fauci also informed the World Health Organization executive board that the US would be joining the COVAX initiative, according to CNBC.

A new preprint suggests some SARS-CoV-2 variants could affect the effectiveness of current vaccines, the Associated Press reports.

In Nature this week: Australian lungfish provides details on the movement of vertebrate life from water to land, and more.