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An analysis using UK Biobank data indicates that the CCR5-Δ32 gene mutations He Jiankui reportedly attempted to introduce into human embryos may be deleterious.

The researchers used circularly permuted Cas9 variants to produce four cytosine and four adenine base editors with an expanded editing window.

With CRISPR being applied to a range of biological problems, researchers are searching for ways to stop its edits, Technology Review reports.

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

In Nature this week: analysis of gut microbiome of colorectal cancer patients, enzymes that block CRISPR editing, and more.

Eighteen researchers call for a temporary stop to all clinical uses of human germline editing in a piece appearing in Nature.

The biotech startup, which had been working with Cas12 and Cas13, has now licensed the recently discovered Cas14 protein from UC Berkeley.

CRISPR technology has made its way around the world, but in the wake of the He Jiankui controversy, the industry is asking what recourse it has against misuse.

For the Future

Rolling Stone calls the University of California, Berkeley's Jennifer Doudna one of the women who is shaping the future.

In Science this week: the synthetic genetic system hachimoji, and more.

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23andMe has launched a new tool that estimates someone's risk of developing severe COVID-19 if infected, Bloomberg reports.

The Guardian reports that Pasteur Institute researchers are halting their development of a SARS-CoV-2 vaccine following disappointing initial results.

The Wall Street Journal reports that an increased number of younger patients have been hospitalized as the new SARS-CoV-2 strain spread across the UK.

In Cell this week: proteomic patterns among COVID-19 affected tissue samples, transcriptome atlas of developing intestines, and more.