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The researchers used circularly permuted Cas9 variants to produce four cytosine and four adenine base editors with an expanded editing window.

With CRISPR being applied to a range of biological problems, researchers are searching for ways to stop its edits, Technology Review reports.

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

This Week in Nature

In Nature this week: analysis of gut microbiome of colorectal cancer patients, enzymes that block CRISPR editing, and more.

Eighteen researchers call for a temporary stop to all clinical uses of human germline editing in a piece appearing in Nature.

The biotech startup, which had been working with Cas12 and Cas13, has now licensed the recently discovered Cas14 protein from UC Berkeley.

CRISPR technology has made its way around the world, but in the wake of the He Jiankui controversy, the industry is asking what recourse it has against misuse.

For the Future

Rolling Stone calls the University of California, Berkeley's Jennifer Doudna one of the women who is shaping the future.

This Week in Science

In Science this week: the synthetic genetic system hachimoji, and more.

Business Insider reports on efforts to apply genetic engineering to cacao plants.

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University of Idaho researchers model the scientific discovery process to examine the link between reproducibility and scientific truth.

A bill passed by a US House of Representatives appropriations subcommittee would give scientific agencies including the National Science Foundation boosts in funding.

Relocating USDA agencies outside of Washington, DC, may make them less effective, critics of the move tell NPR.

In PLOS this week: genes that help Borrelia burgdorferi survive in ticks, CiliaCarta collection of about 1,000 suspected cilia genes, and more.