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Building off ChatGPT Popularity, Generative AI Starts Finding its Place in Genome Informatics
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Bioinformaticians, researchers, and commercial software developers worldwide are trying to harness the power of generative AI for genomics without compromising scientific integrity.

In Brief This Week: UC Berkeley, Biocept, Biocartis, Angle, Twist Bioscience, More

News items for the week of April 17, 2023.

Systematic Approach Identifies, Characterizes Dozens of New Large Serine Recombinases

The recombinases exhibited increased integration efficiency and could be applied to a range of functional genomic and genome engineering applications.

Founder Events Common in Human, Dog Populations, Study Finds

Using a computational method called ASCEND, researchers retraced founder events in hundreds of modern and ancient human populations and dozens of dog breeds.

Study Follows Infant Gut Microbiome Development in Nonindustrialized Hunter-Gatherer Population

Starting with fecal metagenomic and 16S ribosomal RNA gene sequences for dozens of Hadza infants, researchers retraced infant gut microbiome features.

Jan 25, 2022

Metagenomi Raises $175M in Series B Financing Round

Nov 11, 2021

Long-Lived Rockfish Genome Analysis Provides New Clues to Longevity

Oct 20, 2021

Telomere-To-Telomere Consortium Shares Insights From Gapless Human Genome at ASHG
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Jan 15, 2021

Mammoth Biosciences Taking Lead Role in DARPA-Funded Development of Pathogen Detection Tech
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Dec 21, 2020

COVID Assays Using CRISPR, Smartphones Show Potential for At-Home Testing
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Nov 12, 2020

CRISPR Startup Metagenomi Raises $65M in Series A Financing Round

Oct 5, 2020

Berkeley Lights Helps Researchers Connect Genomic, Functional Characteristics of Cells
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Sep 14, 2020

Ansa Biotechnologies Raises $7.9M in Seed Funding

Sep 11, 2020

Patent Board Rules Broad Institute First With Functioning CRISPR System in Eukaryotic Cells

Aug 12, 2020

Mammoth Biosciences Eyes Multiple Applications for Newly Discovered UC Berkeley CRISPR Proteins
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Aug 10, 2020

Newborn Exome Sequencing Shows Potential to Help Find Inborn Errors of Metabolism

Jul 16, 2020

CRISPR Enzyme From Bacteriophage Targets Wider Range of DNA Sequences Than Cas9, Cas12
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Apr 3, 2020

Breast Cancer Subtypes Vary With Indigenous Ancestry in Latin American Women

Mar 17, 2020

Broad Institute Researchers Develop Faster, More Efficient Base Editor

Feb 10, 2020

European Patent Office Upholds UC Berkeley CRISPR Patent

Aug 29, 2019

DoE Awards $64M in Funding to Groups Using Genomics to Study Plants, Microbes

Aug 16, 2019

UCLA to Lead $10M Conservation Genomics Project

Aug 1, 2019

CRISPR Patent Fight Turns Ugly as UC Accuses Broad Researchers of Lying About Claims

Jul 31, 2019

CRISPR Patent Pools Pop Up, But Participation Uncertain as IP Holders Continue Legal Battles
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Jun 25, 2019

CRISPR Patent Fight Between UC Berkeley, Broad Flares Up as USPTO Initiates New Interference

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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.