Tufts

The groups will conduct a study evaluating the benefits of targeted next-generation sequencing in the diagnosis and care of infants with genetic disorders.

Tufts University researchers found a role for miRNA in transmitting stress between generations, the Economist reports.

Using an immunoassay as an initial screening tool saved approximately $36,000 over multiplex PCR panel use alone when performed in a period of high flu prevalence.

This Week in PNAS

In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.

In Genome Research this week: approach for profiling complex genomic rearrangements, sex-biased microRNA expression, and more.

Sourdough-ome

Researchers are using sourdough starter to get a glimpse into the factors and processes that influence the microbiome, NPR reports.

In Nucleic Acids Research this week: improved method for determining RNA structure, approach for detecting microRNAs digitally, and more.

Researchers unearth instances of horizontal gene transfer between bacteria used in making cheese, New Scientist reports.

Tufts scientists and their colleagues called for steps to ensure that disadvantaged groups benefit from genetically based diagnoses and treatments.

Metabolon will work with Johns Hopkins University and Tufts Medical Center to develop and clinically validate the new blood-based diagnostic.

Pages

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.