The institutes will lead a consortium of researchers investigating the molecular underpinnings of diabetic retinopathy, a key cause of blindness.
Investigators are studying samples from a group of 100 patients to try to lock down patterns in circulating tumor DNA that can be used to validate monitoring methods for the clinic.
The project aims to use circulating tumor DNA to monitor drug response and resistance in metastatic melanoma patients in order to guide treatment decisions.
Using meat and clinical samples collected prospectively over a year, researchers found evidence for poultry-to-human transmission of Escherichia coli sequence type 131.
The partners will particularly examine cell-free and exosomal RNAs as potential biomarkers for early-stage pancreatic cancer diagnosis in patients.
In PLOS this week: approach to diagnose hemorrhagic fevers, recessive disease mutations in mixed-breed dogs, and more.
Through prospective pancreatic ductal adenocarcinoma testing, researchers saw germline mutations in new genes and in cases outside of current germline testing criteria.
A new TGen analysis has unraveled breast cancer mutational patterns specific to black women that could help improve outcomes and reduce recurrence.
The partners aim to sequence thousands of tuberculosis bacteria isolates as part of a broader effort to develop personalized treatments for the disease.
Crowdfunding will help move the targeted sequencing-based test through the development process in hopes of commercializing it.
Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.
The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.
ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.
In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.