TGen

The institutes will lead a consortium of researchers investigating the molecular underpinnings of diabetic retinopathy, a key cause of blindness.

Investigators are studying samples from a group of 100 patients to try to lock down patterns in circulating tumor DNA that can be used to validate monitoring methods for the clinic.

The project aims to use circulating tumor DNA to monitor drug response and resistance in metastatic melanoma patients in order to guide treatment decisions.

Using meat and clinical samples collected prospectively over a year, researchers found evidence for poultry-to-human transmission of Escherichia coli sequence type 131.

The partners will particularly examine cell-free and exosomal RNAs as potential biomarkers for early-stage pancreatic cancer diagnosis in patients.

This Week in PLOS

In PLOS this week: approach to diagnose hemorrhagic fevers, recessive disease mutations in mixed-breed dogs, and more.

Through prospective pancreatic ductal adenocarcinoma testing, researchers saw germline mutations in new genes and in cases outside of current germline testing criteria.

A new TGen analysis has unraveled breast cancer mutational patterns specific to black women that could help improve outcomes and reduce recurrence.

The partners aim to sequence thousands of tuberculosis bacteria isolates as part of a broader effort to develop personalized treatments for the disease.

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New results from the NASA Twins Study indicate that the immune system may rev up when in space, the Washington Post reports.

Kelvin Droegemeier, the new science advisor, spoke at the American Association for the Advancement of Science meeting, Geekwire reports.

In PNAS this week: whole-genome assembly for the white shark, paper-based microfluidic method for detecting the malaria parasite, and more.

The World Health Organization has announced the members of its gene-editing committee, according to NPR.