Technical University Munich
Osteoarthritis Risk Genes, Treatment Targets Unearthed in GWAS Meta-Analysis
Researchers identified 962 osteoarthritis risk variants and potentially targetable effector genes using genetic data for 489,975 cases and nearly 1.5 million unaffected controls.
Restless Leg Syndrome-Related Genetic Loci Identified in GWAS Meta-Analysis
Researchers tracked down genetic risk loci for restless leg syndrome, providing insights to predict disease risk and inform potential treatment approaches.
Infant Gut Microbiome Study Highlights Development, Rhythmicity Over Time
Researchers saw age-related effects on the infant gut microbial community development, along with diet-related differences in fecal metabolite patterns.
Type 2 Diabetes, Osteoarthritis Comorbidity Traced to Obesity-Related Processes
Researchers turned to genotyping, multiomics, and functional studies to untangle the processes contributing to type 2 diabetes and hip/knee osteoarthritis.
Proteomic Study of SARS-CoV-2, SARS-CoV Infections Points to Potential Drug Targets
Researchers profiled interactions of the viruses with a lung-derived human cell line and effects on the transcriptome, proteome, ubiquitinome, and phosphoproteome.