Organization: TCGA The Decade in Genomics: CRISPR, Single Cells, Long Reads, Clinical and Consumer Applications Premium GenomeWeb asked a number of prominent researchers in the field via email about their top picks for notable developments or achievements in genomics during the 2010s. Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis Researchers re-examined whole-genome and whole-transcriptome sequencing TCGA studies from 33 cancer types and found unique microbial signatures. Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression Signature An international team documented TP53 mutation-related genomic changes across dozens of cancer types using data generated with five platforms for the Cancer Genome Atlas project. Mount Sinai Team Demonstrates Abilities of Proteogenomic Analysis Software Premium In a recent study, the researchers used the software to analyze multi-omic ovarian cancer data generated by the TCGA and CPTAC initiatives. Gastric Cancer Analysis in Young Populations Identifies Four Subtypes The subtypes — which were distinguished from one another using proteomic data — were associated with proliferation, immune response, metabolism, and invasion. Jan 14, 2019 Tumor Hypoxia Associated With Cancer Driver Mutation Signatures in 19 Tumor Types Jan 10, 2019 Potential Prognostic Signature Described in HPV-Positive Squamous Cell Carcinomas Jan 3, 2019 Glioblastoma Pathway Signatures, Treatment Responses Differ Between Male, Female Patients Oct 25, 2018 Cancer Chromatin Maps Reveal Regulatory Features, Subtype Differences Apr 6, 2018 Pan-Cancer Analysis Identifies Mutational Hotspots at the Protein Level Premium Apr 5, 2018 TCGA's Pan-Cancer Atlas Papers Examine Clustering of Tumors, Key Alterations Apr 3, 2018 TCGA Pan-Cancer Studies Describe New Tumor Features, Subtypes Dec 4, 2017 Baylor Researchers Develop Tool for Analyzing TCGA, CPTAC Datasets Premium Oct 19, 2017 Evolutionary Analysis Reveals Number, Nature of Mutations Under Positive Selection in Cancer Jun 15, 2017 Data Analytics Startup Medley Genomics Targets Genomic Heterogeneity; Initial Focus on Cancer Premium Jan 23, 2017 Cervical Cancer Analysis Yields Novel Changes, Therapeutic Targets Jan 4, 2017 Esophageal Cancer Genomic Analysis Uncovers Disease Subtypes Jul 12, 2016 Red Hair-Linked Gene Variants Also Associated With Increased Skin Cancer Mutations Jun 30, 2016 Annai Preps NGS Data Management Platform for Formal Launch; Unveils Early Customer Premium Jan 28, 2016 Integrated Glioma Analysis Uncovers Epigenetics-based Subtypes Dec 22, 2015 WUSTL Team Finds Inherited Mutations Common Across Cancer Types Nov 5, 2015 Molecular Analysis Places Primary Prostate Tumors Into Number of Subtypes Nov 5, 2015 TCGA Analysis Points to Kidney Cancer Subtypes With Prognosis, Treatment Clues Jun 18, 2015 TCGA Defines New Subtypes for Cutaneous Melanoma Jun 11, 2015 NEJM Studies Define New Molecular Subtypes for Glioma Premium Load More Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.