The Decade in Genomics: CRISPR, Single Cells, Long Reads, Clinical and Consumer Applications
GenomeWeb asked a number of prominent researchers in the field via email about their top picks for notable developments or achievements in genomics during the 2010s.
Microbiome-Based Cancer Dx Emerges From Cancer Genome Atlas Reanalysis
Researchers re-examined whole-genome and whole-transcriptome sequencing TCGA studies from 33 cancer types and found unique microbial signatures.
Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression Signature
An international team documented TP53 mutation-related genomic changes across dozens of cancer types using data generated with five platforms for the Cancer Genome Atlas project.
In a recent study, the researchers used the software to analyze multi-omic ovarian cancer data generated by the TCGA and CPTAC initiatives.
Gastric Cancer Analysis in Young Populations Identifies Four Subtypes
The subtypes — which were distinguished from one another using proteomic data — were associated with proliferation, immune response, metabolism, and invasion.