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Researchers reached clinical diagnoses in 35 percent of cases undergoing evaluation over 20 months, sometimes leading to treatment changes.

The company is developing a blood-based liquid biopsy test based on the method to monitor 5-hydroxymethylcytosine levels in cell-free tumor DNA.  

Genetic and phenotypic data for Million Veteran Program participants led to loss-of-function changes in a gene inhibited by cilostazol.

The researchers were able to measure the fitness effects of thousands of natural genetic variants in yeast at single-base resolution.

Individuals' 'exposomes' indicated that people come into contact with thousands of species and chemicals over time and that exposures vary by locale and season.

Researchers profiled the composition and gene content of microbial communities in mouth, gut, and vaginal samples collected from 10 pregnant women.

In Cell this week: genomic analysis of abdominal aortic aneurysm, effect of probiotics on the microbiome, and more.

Population geneticist Luigi Luca Cavalli-Sforza has died, The Scientist reports.

The framework, called HEAL, could be used as an early screening test for AAA and as a personal health management tool. In addition, it may be applicable to other complex diseases.

A phylogenetic analysis that included multiple samples per patient suggests overlapping driver mutations make their way into multiple metastases in each patient.

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The Centers for Disease Control and Prevention estimates more people get sick and die from drug-resistant germs than previously thought, the Washington Post reports.

According to the Associated Press, three universities and a healthcare institution are sharing a gift of $1 billion.

New rules seek to limit the type of scientific and medical research that can be used to guide public health regulations, the New York Times reports.

In Nature this week: FreeHi-C approach simulates Hi-C data from interacting genome fragments, and more.