Independent research teams from the University of Washington and Stanford University have developed methods for doing direct haplotyping that employ large insert cloning and microfluidics, respectively.
Using chromatin immunoprecipitation sequencing, RNA sequencing, and other approaches, researchers from Stanford University have tracked down thousands of enhancers near genes that are inactive in human embryonic stem cells but which become active during early stages of development.
The assay, which is based on melt curve analysis, can currently detect and discriminate between nearly 40 important clinical bacterial species, and may eventually be able to test for more than 100 such species, according to the project's lead scientist.
The US Supreme Court will review a case in which Stanford University sued Roche for IP infringement, arguing federal legislation gives the school rights to PCR technology that was developed with NIH funds.
By compiling and analyzing data on thousands of disease-associated SNPs, a California research team has garnered evidence suggesting synonymous SNPs are as likely to be associated with disease as non-synonymous SNPs.
With the assay, the Stanford researchers have begun examining protein phosphorylation levels in a variety of cancer types. The team has also entered into collaborations with several pharmaceutical firms to investigate the effects of therapeutic agents on protein phosphorylation levels in tumor cells.
Grants awarded to GE Global Research and Stanford University may help address many of the inherent technical difficulties of isolating, amplifying, and sequencing genetic material from microorganisms that colonize various parts of the human body.