Stanford
Two methods for increasing the stability of cell-free DNA and for minimizing its cellular uptake could lead to higher cfDNA yields and improved cancer tests.
By mapping individual cells to a scRNA-seq atlas, the new computational method seeks to fill in missing pieces in transcriptomes and advance cancer drug discovery.
APOE Missense Variant Linked to Increased Alzheimer's Disease Risk in African Americans
A case-control study found that the APOE ε3[R145C] variant, seen in 4 percent of African Americans, increases AD risk in individuals with the ε3/ε4 genotype.
Cardiac-Related Consequences of Alcohol Flushing Genetic Variant Reduced by Drug
With endothelial cells derived from induced pluripotent stem cells, researchers tracked functional changes and potential treatment targets in alcohol flushing variant carriers.
Ulcerative Colitis Single-Cell Tissue Atlas Gives Insight Into Treatment Response
Researchers used a tissue atlas they created to analyze cell types that behave differently with TNF inhibitors treatment.