Stanford Medical Genome Initiative Develops Best Practices, Standards for Clinical Whole-Genome Sequencing Premium The nine-institute organization, founded by Illumina, recently issued guidelines for the interpretation and reporting of clinical whole-genome sequencing tests. Polygenic Risk Score Performance Improved With Expression-Related Rare Variant Insights Using an independent outlier gene count score, investigators found that rare variants linked to gene expression outlier effects can improve polygenic risk score predictions. Single-Cell Transcriptome Resource From Human Cell Atlas Team Yields Immune, Disease Insights Researchers tallied expression features across hundreds of cell types with single-cell or -nucleus sequencing on hundreds of thousands of cells from numerous individuals. Mirvie Developing Cell-Free RNA Blood Tests to Predict Pregnancy Complications Premium The South San Francisco-based startup recently published two studies showing the performance of its tests for predicting preterm birth and preeclampsia. Proof-of-Principle Study Points to Possibility of Monitoring Pediatric ALL With Plasma Samples Capture-based blood plasma sequencing helped track disease persistence or relapse and identify microbes that may cause infection in the immunosuppressed patients. Apr 8, 2022 Non-Western Populations Underrepresented in Microbiome Databases; Partnerships Could Boost Numbers Premium Apr 7, 2022 New Liquid Biopsy Method Infers RNA Expression From DNA Fragmentation Analysis Premium Mar 21, 2022 Ancient, Present-Day Indigenous Ohlone Tribe Members in California Share Distinct Genetic Ancestry Mar 17, 2022 Several Causal Variants Found at Genetic Loci Influencing Gene Expression in Humans Feb 22, 2022 Metagenomic Analysis of Urban, Rural South African Women Reveals Gut Microbiomes in Transition Jan 27, 2022 As Genetic Variant Reanalysis Needs Grow, Researchers Turn to Automation Premium Jan 21, 2022 Despite Record Speed, Nanopore Sequencing Faces Challenges for Use in Routine Diagnostics Premium Oct 27, 2021 Polygenic Risk Scores Edge Toward Clinic, Though Disease Prediction Utility Questions Linger Premium Sep 29, 2021 Metagenomic Infectious Disease Sequencing Test Repurposed for Cancer Detection From CSF Samples Premium Sep 15, 2021 Deepcell Partners With Stanford University on Human Cell Atlas Project Sep 3, 2021 CRISPR Researchers Engineer Highly Efficient Miniature Cas System Jul 26, 2021 Foresight Diagnostics Commercializing PhasED-seq Liquid Biopsy Tech for Improved MRD Detection Premium Jul 14, 2021 Microbiome-Focused Metabolomics Pipeline Helps Characterize Gut Bacteria Jun 25, 2021 Seasonal Influenza Vaccination Leads to Immune Cell Epigenomic Changes Jun 2, 2021 Foresight Diagnostics Raises $12.5M in Series A to Commercialize MRD Detection Tech May 24, 2021 AACR Presentations Highlight Power of Large Tumor Atlases in Studies of Cancer Progression Premium May 5, 2021 Maternal Blood Proteomic, Metabolomic Changes Could Predict Onset of Labor Apr 28, 2021 DermTech Partners With Stanford School of Medicine to Study Chronic Skin Disorder Apr 12, 2021 Amazon to Give Out $12M Under Next Phase of AWS Diagnostics Development Initiative Mar 25, 2021 Wild Animal Gut Microbiomes Reveal New Species, Ties to Host Traits Load More Breaking News Canadian Healthcare Providers, Policymakers Value Different Aspects of Clinical Genomic Sequencing New Products Posted to GenomeWeb: Oxford Nanopore, Bio-Rad, NanoString, More People in the News at OraSure, Element Biosciences, Micronoma, More Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study The Scan Blend of Omicron With Delta The Associated Press reports that currently circulating Omicron variants have some features previously seen in the Delta variant. Limited Contrast The New York Times reports that there is a shortage of a contrast agent used for some medical scans. Pig Improvement Farmers in China are using genetics to improve their hog herds, according to Reuters. Science Papers Present Way to Molecularly Classify Prostate Cancer, Saliva-Based SARS-CoV-2 Test, More In Science this week: approach to molecularly classify prostate tumors, saliva-based test for SARS-CoV-2, and more.