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Stanford University's Allison Kurian and her colleagues found that women with pathogenic variants were more likely to undergo a bilateral mastectomy.

This Week in PNAS

In PNAS this week: plant protein engineering, Angelman syndrome, and more.

In patients with a range of rare diseases, RNA sequencing in blood had a 7.5 percent diagnostic rate and identified candidate genes in 16.7 percent of cases.

The studies, which used multi-omic approaches, are part of the integrative Human Microbiome Project (iHMP) — the second phase of the Human Microbiome Project.

Interest Piqued

Stanford University's William Hurlbut says fertility clinics and others reached out to He Jiankui after his embryonic gene-editing announcement, the AP reports.

Cancer Moonshot-funded teams are profiling pre-cancers in an effort to establish targeted treatment, detection, and prevention methods that can be applied before cancers form.

A Personal Effort

CNN reports on Stanford University's Ron Davis' quest to study chronic fatigue syndrome.

Research led by Stanford's Mike Snyder has inspired a new company, Q Bio, offering genomic and other analyses, and longitudinal tests to track individuals' health.

NPR writes that, despite concerns, researchers don't know enough about genetics to make "designer babies."

This Week in PNAS

In PNAS this week: core Pseudomonas aeruginosa genome, study of ancient Paget's disease of the bone, and more.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.