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St. Jude Children's Research Hospital has launched a website for published research results from its Pediatric Cancer Genome sequencing project with Washington University.

Members of the Pediatric Cancer Genome Project have developed and validated a new algorithm to track down structural variation in cancer genomes based on soft-clipping data generated when sequence reads are partially aligned to a reference genome.

Researchers at St. Jude Children's Research Hospital found that even limited DNA sequencing can provide clues for more effective ALL treatments, and believe that more comprehensive sequencing could deliver additional clinically relevant results.

During a plenary session at the American Association for Cancer Research annual meeting this week, St. Jude's Children's Research Hospital Scientific Director James Downing discussed preliminary findings from the pediatric cancer genome project that his group is doing in conjunction with investigators at Washington University.

T-cell receptor sequencing is "a long way from being used clinically," said Robert Holt, head of sequencing at the BC Cancer Agency's Genome Sciences Center and senior author of a recent paper on the subject.

Insight is developing the tests using TaqMan probes on Life Technologies' ABI 7500 Fast Dx real-time PCR system to help physicians monitor cancer patients for mutations and upregulation in the ALK gene in order to make more effective treatment decisions.

In addition to developing a test to monitor ALK gene mutation status, Insight is working on a companion diagnostic directed at ALK.


New US Department of Commerce rules will affect supercomputing in China, according to the Wall Street Journal.

A new analysis finds that it will be more than a century until female computer scientists publish at the same rate as their male counterparts, ScienceInsider reports.

Broad Institute researchers describe an approach they've dubbed "DNA microscopy."

In PLOS this week: epigenetic changes following hepatitis C virus treatment, metagenomic analysis of Ugandan children with febrile illness, and more.