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The funds will be used to expand the PharmGKB database and support the activities of the Clinical Pharmacogenetics Implementation Consortium.

The funding will support work identifying the mechanisms underlying the differential responses among pediatric and adult ALL patients to therapy.

Researchers found alterations that activate the RAS-MAPK pathway in 18 of 23 relapse neuroblastoma tumors tested.

A missense change in CDKN2A turned up through a genome-wide association study involving thousands of childhood acute lymphoblastic leukemia cases and controls.

By combining structural variants with read depth change data, the software is able to find CNAs in whole-genome sequence that other methods miss.

The group has developed tables that match genotype, phenotype, and clinical recommendations to help inform therapy choices at the point of care. 

Whole-exome sequencing shows that relapse in acute lymphoblastic leukemia is driven by cancer cells with sneakier, rather than more numerous, mutations.

Researchers at St. Jude and elsewhere identified a promoter SNP associated with peripheral neuropathy in vincristine-treated children with acute lymphoblastic leukemia.

By testing hundreds of children with brain tumors who were treated with cisplatin, researchers identified risk variants related to cisplatin ototoxicity.

NEWYORK (GenomeWeb) – Personalized medicine proponents have long argued that pharmacogenomics can increase drug efficacy and reduce dangerous adverse outcomes, especially if PGx information is collected and stored preemptively so that it can be available at the point of prescribing and useful in

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The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.

The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.

New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.

In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.