St. Jude
Gates Foundation Awards Multiple Dx, Omics Grants in August and September
Awardees include Imperial College London, the Africa Health Research Institute, Mylab, CHOP, and the Task Force for Global Health, among others.
Childhood Acute Lymphoblastic Leukemia Subtypes, Prognostic Features Uncovered in Genomic Study
Researchers identified 15 subtypes of T-lineage ALL, along with mutation, expression, and regulatory shifts providing development and prognostic clues.
Polygenic Risk Scores Help Inform Adult Cancer Risk in Childhood Cancer Survivors
Researchers found that cancer-specific PRS and individuals' history of high radiation treatment could help predict development of a handful of adult cancer types.
Cancer Predisposition Variants Increase Secondary Cancer Mortality Risk in Pediatric Survivors
In data from childhood cancer survivors, researchers saw an uptick in secondary cancer-related mortality in those with cancer-linked germline variants.
Elevated Epigenetic Aging Puts Childhood Cancer Survivors at Risk of Obesity, Other Conditions
A cross-sectional study of epigenetic aging in 2,846 pediatric cancer survivors also found that the rate at which epigenetic aging changed differed between age groups.