St. Jude

Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression. 

Children's Genomics

US News and World Report takes a look at genomics' role at pediatric hospitals.

Expression profiles of 1,900 B-cell acute lymphoblastic leukemia cases point to the presence of a subtype marked by rearrangements in transcription factor DUX4.

The partners will exchange all information they have on genetic mutations leading to cancer with an eye toward accelerating research and drug discovery efforts.

Scientists introduced an indel to a promoter region to mimic a benign, naturally-occurring mutation that activated fetal hemoglobin production.

Researchers from St. Jude Children's and the German Cancer Research Center used methylation and gene expression analyses to uncover the subtypes.

The deal could bolster Genelex's business, but CEO Kristine Ashcraft is hopeful that the integration with Epic Systems a sign of growing acceptance of pharmacogenetic testing.

With ProteinPaint, investigators can visualize sequence mutations, gene fusions, and RNA expression to interpret patterns in germline and tumor samples.

More than 8 percent of pediatric cancer cases considered by the Pediatric Cancer Genome Project carried mutations affecting established cancer risk genes. 

Exome and targeted gene sequencing uncovered germline variations in the ETV6 gene that may increase susceptibility to acute lymphoblastic leukemia.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.