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Scripps Research Institute

Researchers saw signs of an unreported Zika virus outbreak in Cuba in 2017, well after the documented decline in new cases in Brazil and other parts of the world.

Pushed Out

ScienceInsider reports Floyd Romesberg has been forced out from the Scripps Research Institute.

In PNAS this week: role for exosomes in neuronal circuit development, tuberculosis pathogen enzymes, and more.

An analysis of B cell adaptive immune receptor sequences in 10 individuals uncovered exceptionally diverse antibody repertoires with a subset of shared antibody clonotypes.

New Bases, New Drugs

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.

There are some deep divisions between the three main databases, some due to competitive pressures and others because of the nature of metabolomics.

In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.

Don't Touch

Two research teams find a role for PIEZO2 in touch sensitivity after injury and inflammation.

In PNAS this week: history and genetic diversity of the scarlet macaw, approach for predicting human flu virus evolution, and more.

The team found that constrained regions of the noncoding genome are up to 52-fold enriched for known pathogenic variants as compared to unconstrained regions. 

Pages

The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.