Sanger Institute

Researchers identified immune activity changes in first-trimester placenta and decidua samples profiled through single-cell RNA sequencing.

The Darwin Tree of Life Project aims to sequence the genetic codes of 66,000 different species in the UK as part of the Earth BioGenome Project.

An investigation found no evidence of bullying or gender discrimination, but did find management flaws at the Wellcome Trust Sanger Institute, the Guardian reports.

The researchers found that genes whose transcription in response to an immune challenge diverged across species also varied between single cells.

Researchers saw frequent somatic mutations in esophageal tissue from nine individuals, including mutations under positive selection in 14 oncogenes.

In combination with other clinical data, the genomic subtypes were able to predict patients' outcomes and could be used to help guide treatments.

A new study suggests that common variants influence neurodevelopmental disorder risk and the way the conditions manifestation themselves.

The VGP released its first 15 high-quality reference genome assemblies today, which are part of the project's first phase to sequence 260 vertebrate genomes.

Researchers were able to estimate the number of active hematopoietic stem cells based on the number of somatic mutations present.

The Guardian reports that senior management at the Wellcome Sanger Institute is under investigation after allegations of bullying and discrimination.

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Customers might want to consider what they might learn about their risk of diseases like Alzheimer's before snagging the genetic testing kits that are on many gift guides this year, NJ.com writes.

The Wall Street Journal reports there is uncertainty surrounding whether He Jiankui's embryo editing did what he said it did.

Stat News reports that the pause on procuring fetal tissue for intramural US National Institutes of Health research will soon affect additional labs there.

In Nature this week: genomic analysis of the invasive fall webworm, amp of constrained coding regions within the human genome, and more.