Sanger Institute | GenomeWeb

Sanger Institute

The researchers said their one-step, inducible, multiplex gene knockdown and gene knockout platforms can be used in many differentiated cell types.

The Bridget Ogilvie Building will house sequencing facilities, and the Biodata Innovation Centre will host genomic startups.

Two new studies are exploring genomic features and population variation in the river blindness-causing parasite Onchocerca volvulus.

A sequencing study suggests multidrug-resistant Mycobacterium abscessus bacteria are often passed between people, not acquired from the environment.

Two independent research teams linked plasmepsin 2 and plasmepsin 3 gene amplifications to piperaquine resistance.

By analyzing mutations in tumors from a broad swath of tobacco smoke-related cancer types, investigators identified more than two-dozen mutational signatures.

The researchers will use single-cell genomics and other approaches to generate information that could ultimately be used to diagnose, monitor, and treat disease.

An international team analyzed the genomes of 65 wild-born chimpanzees and 10 bonobos to uncover evidence of gene flow.

Using sequence data for more than 1,800 Salmonella enterica serovar Typhi isolates, researchers identified 68 SNPs to trace the bug to its geographical source. 

Genome sequencing suggests secondary tumors present after ionizing radiation treatment tend to contain numerous deletions and balancing inversions.

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In PNAS this week: carbapenem resistance in Enterobacteriaceae, selection against educational attainment-linked variants, and more.

Technology Review points out that a new US presidential science advisor hasn't been selected.

Researchers find that blood tests might be able to help determine severity of a concussion, Wired reports.

President-elect Donald Trump considers other candidates for director of the National Institutes of Health, Nature News reports.