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Distinct alterations of the APP gene in Alzheimer's patients appear to depend on reverse transcriptase, suggesting HIV antiretroviral drugs as a potential new treatment.

In PNAS this week: rise of copy-number variants during neurogenesis, genetic and phenotypic variation in Pseudomonas aeruginosa, and more.

Using a new machine-learning approach, researchers from the Sanford Burnham Prebys Medical Discovery Institute analyzed brain cells obtained from mice during neurogenesis.

The researchers identified 122 potential immune response drivers that could serve as targets for drug research efforts.

The money was provided by real estate developer and philanthropist Conrad Prebys and will be used to accelerate the delivery of new treatments to improve human health.

The partners will screen for molecules that could revive metabolic activity in heart tissue damaged by cardiovascular disease or failure.

Originally published Oct. 9.
NEW YORK (GenomeWeb) – Long non-coding RNAs (lncRNA), molecules previously thought to play no role in cellular or disease development, may provide researchers a new avenue for developing a non-invasive diagnostic for prostate cancer.

The Broad Institute confirmed that it is laying off 27 employees as the National Institutes of Health stopped funding for a program, and the institute separately decided to refocus its therapeutic development efforts.

While variants in the gene FTO have previously been associated with a propensity toward obesity, the University of Chicago's Marcelo Nóbrega and colleagues reported in Nature this week that those obesity-linked variants in FTO actually

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.