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Nov 21, 2018

Alzheimer's Disease Gene Undergoes Somatic Recombination in Neurons

Distinct alterations of the APP gene in Alzheimer's patients appear to depend on reverse transcriptase, suggesting HIV antiretroviral drugs as a potential new treatment.

Oct 02, 2018

This Week in PNAS

In PNAS this week: rise of copy-number variants during neurogenesis, genetic and phenotypic variation in Pseudomonas aeruginosa, and more.

Sep 25, 2018

Single-Cell Analysis Uncovers Thousands of CNVs That Arise During Development

Using a new machine-learning approach, researchers from the Sanford Burnham Prebys Medical Discovery Institute analyzed brain cells obtained from mice during neurogenesis.

Jul 22, 2016

Sanford Burnham Researchers ID More Than 100 Genetic Regions Affecting Immune Response to Cancer

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The researchers identified 122 potential immune response drivers that could serve as targets for drug research efforts.

Jun 24, 2015

Sanford-Burnham Receives $100M Donation, Changes Name

The money was provided by real estate developer and philanthropist Conrad Prebys and will be used to accelerate the delivery of new treatments to improve human health.

May 28, 2015

Takeda Partners with Sanford-Burnham on Heart Failure Research

The partners will screen for molecules that could revive metabolic activity in heart tissue damaged by cardiovascular disease or failure.

Oct 15, 2014

Researchers Explore Using Long Non-coding RNAs as Non-invasive Marker for Prostate Cancer Testing

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Originally published Oct. 9.
NEW YORK (GenomeWeb) – Long non-coding RNAs (lncRNA), molecules previously thought to play no role in cellular or disease development, may provide researchers a new avenue for developing a non-invasive diagnostic for prostate cancer.

May 12, 2014

Broad Institute Lays off 27 Amid Ending of NIH Program, Shift in Therapeutics Development Focus

NEW YORK (GenomeWeb) – The Broad Institute confirmed that it is laying off 27 employees as the National Institutes of Health stopped funding for a program, and the institute separately decided to refocus its therapeutic development efforts.

Mar 13, 2014

Genomics in the Journals

NEW YORK (GenomeWeb News) – While variants in the gene FTO have previously been associated with a propensity toward obesity, the University of Chicago's Marcelo Nóbrega and colleagues reported in Nature this week that those obesity-linked variants in FTO actually

Nov 12, 2013

USAF Funds Sanford-Burnham Chemical Screening Initiative

NEW YORK (GenomeWeb News) – Sanford-Burhnam Medical research Institute said today it has received a grant from the US Department of the Air Force to use cell-based assays to study the potential toxicity of large collections of chemicals.

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The Scan

Faster Profiles

The Washington Post reports on a Federal Bureau of Investigation plan to place rapid DNA analyzers at booking stations around the country.

Standards Needed

In an editorial, officials from scientific societies in the US and China call for the international community to develop criteria and standards for human germline editing.

Conflict Search

The US National Institutes of Health is to review studies that have received private support for conflicts of interest, according to the New York Times.

This Week in Science

In Science this week: the PsychENCODE Consortium reports on the molecular mechanisms of neuropsychiatric disorders, and more.

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