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Distinct alterations of the APP gene in Alzheimer's patients appear to depend on reverse transcriptase, suggesting HIV antiretroviral drugs as a potential new treatment.

In PNAS this week: rise of copy-number variants during neurogenesis, genetic and phenotypic variation in Pseudomonas aeruginosa, and more.

Using a new machine-learning approach, researchers from the Sanford Burnham Prebys Medical Discovery Institute analyzed brain cells obtained from mice during neurogenesis.

The researchers identified 122 potential immune response drivers that could serve as targets for drug research efforts.

The money was provided by real estate developer and philanthropist Conrad Prebys and will be used to accelerate the delivery of new treatments to improve human health.

The partners will screen for molecules that could revive metabolic activity in heart tissue damaged by cardiovascular disease or failure.

Originally published Oct. 9.
NEW YORK (GenomeWeb) – Long non-coding RNAs (lncRNA), molecules previously thought to play no role in cellular or disease development, may provide researchers a new avenue for developing a non-invasive diagnostic for prostate cancer.

The Broad Institute confirmed that it is laying off 27 employees as the National Institutes of Health stopped funding for a program, and the institute separately decided to refocus its therapeutic development efforts.

While variants in the gene FTO have previously been associated with a propensity toward obesity, the University of Chicago's Marcelo Nóbrega and colleagues reported in Nature this week that those obesity-linked variants in FTO actually

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According to BBC News, the global vaccine-sharing initiative has sent its first shipment, which arrived in Ghana this week.

CNN reports that a US Food and Drug Administration document says Johnson & Johnson's SARS-CoV-2 vaccine meets the requirements to receive an Emergency Use Authorization.

Researchers in France are developing a new, fast test for SARS-CoV-2 that initial testing indicates may be highly accurate, the Guardian says.

In Cell this week: analysis of fitness patterns among SARS-CoV-2 isolates, single-cell transcriptome analysis of immune features in COVID-19, and more.