Salk Institute Role of Super-Enhancers in Triggering Pancreatic Cancer Tumor Growth Explored in Study Investigators at the Salk Institute for Biological Studies identified DNA regulatory regions that lead to human pancreatic cancer cell line growth. New Imaging Method Enables Multiplexed Spatial Gene Expression Analysis in Plants Premium Developed by Salk Institute researchers, PHYTOMap can profile expression of multiple genes within whole-mount plant tissue at a cellular level. Center for Multiomic Human Brain Atlas to Tackle Methylation, Gene Expression for $500M NIH Project Premium The Salk Institute for Biological Studies is leading this effort as a key part of NIH's new BRAIN Initiative Cell Atlas Network. NIH Launches $500M Effort to Map Cells of the Human Brain The BRAIN Initiative Cell Atlas Network (BICAN) will rely heavily on single-cell sequencing and bioinformatics to create brain cell atlases and maps of cell interactions. ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization In more than a dozen new papers, ENCODE researchers reported on analyses of the human and mouse genomes, using new data types and additional tissues. Aug 28, 2019 CRISPR Researchers Develop First In Vivo Editing System Targeting Non-Coding DNA Sep 10, 2018 Noncoding Structural Variants Highlighted in Integrated Cancer Genome Analysis Apr 16, 2018 Bioinformatics Pipeline Annotates CRISPR Repeats, Cas Genes; Assembles Data in One Repository Premium Mar 23, 2018 CRISPR Startup Arbor Biotechnologies, Salk Institute Concurrently Discover New Cas13d Enzyme Premium Mar 22, 2018 Early Life Experiences Affect Retrotransposon Accumulation in Mouse Brains Jan 16, 2018 Salk Institute, Indivumed Enter Research Partnership Dec 7, 2017 Researchers Use CRISPR to Epigenetically Alter Disease Phenotypes in Mice Oct 24, 2017 NIH Announces BRAIN Initiative Grants for 2017 Aug 10, 2017 Neuronal Subtypes Revealed Using Single-Cell Methylation Sequencing Jul 28, 2017 Chromatin Structure Less Organized Than Textbooks Say, According to New Study Jan 24, 2017 NSF, USDA Award Microbiome Research Grants Dec 6, 2016 Functional Microprotein Characterized in Human Cells Sep 12, 2016 L1s Contribute to Genomic Diversity of Healthy Somatic Brain Cells Jul 18, 2016 Arabidopsis Studies Tap 1,001 Genomes Data to Explore Genomic, Epigenomic, Speciation History Sep 18, 2015 Researchers Find Age-Related Protein Changes Differ Across Organs in Rats Jun 1, 2015 Human Methylome Map Reveals Variations by Tissue, Non-Canonical Methylation Apr 23, 2015 Salk Scientists Develop Method to Edit Mutations in Germline Mitochondrial DNA Premium Nov 18, 2014 Study Sees Transcriptional Differences in Mouse, Human Tissues Jun 3, 2014 Salk Nets $25M Gift, Closes in on $300M Fundraising Goal May 22, 2014 Salk Lands $3M for Glenn Center for Aging Research Load More Breaking News BostonGene, Johns Hopkins University Partner for Multiple Cancer Clinical Research Projects KromaTid, Noble Life Sciences Ink Distribution, OEM Agreement Promega, GlaxoSmithKline to Develop Microsatellite Instability Companion Diagnostic Kit ZeptoMetrix Quality Control Products Receive IVDR Certification Verily Awarded CDC Contract for Wastewater Surveillance The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.