Sage Bionetworks

Researchers used CRISPR to engineer mice that have multiple genetic variants associated with late-onset AD to facilitate research into biomarkers and treatments.

By analyzing genomic data from nearly 590,000 apparently healthy individuals, researchers uncovered 13 carriers of serious Mendelian disease mutations.

NEW YORK (GenomeWeb) – The organizers of the Dialogue on Reverse Engineering Assessment and Methods (DREAM) project and Sage Bionetworks in collaboration with the Broad Institute, MD Anderson Cancer Center, Rice University, and the Global CEO Initiative for Alzheimer's Disease, launched three new

NEWYORK (GenomeWeb) – In his presentation at the Bio-IT World conference last week, Lincoln Stein, director of informatics and bio-computing at the Ontario Institute for Cancer Research and a professor of molecular genetics at the University of Toronto, discussed efforts to build the Cancer Genom

NEW YORK (GenomeWeb News) – A group of bioinformatics and technology-focused firms and institutes that challenges informatics researchers to solve specific problems, has issued a new challenge to spur investigators to develop better methods for identifying cancer-associated mutations.

NEW YORK (GenomeWeb News) – Researchers from Seattle's Sage Bionetworks, the University of Chicago, the Children's Hospital Oakland Research Institute, and elsewhere reported today that they have detected a new cholesterol-related locus with apparent ties to the risk of muscle-related side effect

Starting this fall, researchers will use an online system developed by Sage Bionetworks to at once collaboratively share data and compete to develop a genetic predictor that can identify rheumatoid arthritis patients who are likely to respond to immunosuppressive anti-TNF therapi

NEW YORK (GenomeWeb News) – A group of federal, academic, and industry partners in the US have launched a new challenge to spur the development of new computational tools for predicting patient responses to certain drugs and chemicals based on their genomes, Sage Bionetworks said today.

This week, the organizers of the annual Dialogue for Reverse Engineering Assessment and Methods and Sage Bionetworks announced that they will run four computational challenges this year focused on oncology, toxicology, and cell modeling.

NEW YORK (GenomeWeb News) – Late-onset Alzheimer's disease is linked to potentially targetable changes to specific pathways and processes in the brain, according to a new molecular network-based analysis of the condition.

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Researchers in the UK and Australia uncover genetic links between BMI and depression, the Guardian reports.

The Verge details the account of an academic who alleges her university retaliated against her after she complained of sexual harassment by her supervisor.

The New York Times writes that natural history museums are helping round out genetic studies with older specimens.

In PNAS this week: artemisinin resistance mutations in malaria parasites, ant-plant interactions over time, and more.