The LOHGIC algorithm is currently being used to analyze tumor sequencing assay results as part of the Rutgers Cancer Institute's precision medicine program.
The approach, published earlier this week in Nature Biomedical Engineering, uses long-adapter single-strand oligonucleotide (LASSO) probes.
The researchers uncovered four Tourette disorder risk genes through exome sequencing of parent-child trios, and estimated there could be hundreds more.
Two researchers devised a protocol to sequence DNA from ancient samples and tested it on 100-year-old museum specimens.
The agency is funding genome sequencing and analysis centers to research the genomic basis of common diseases, as well as ongoing rare disease research.
A study in Molecular Cell shows CRISPR-Cas9-like genome editing in human cells and suggests one protein could be an RNA-guided, RNA-cleaving endonuclease.
With the award, the Rutgers University's Human Genetics Institute of New Jersey unit will provide pluripotent stem cell derivation and quality control services.
The new workflow, which was validated across three separate laboratories in New Jersey, is a critical step toward standardizing the use of RNA-seq in clinical genomics.
The oncology data warehouse started by the Moffitt Cancer Center and Ohio State University Comprehensive Cancer Center now has nine members.
The award will go to David Alland to create an Ebola test using the same technology as a TB assay marketed by Cepheid.
A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.
Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.
In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.
A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.