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Radboud University Medical Centre

While microarrays are quickly replacing traditional karyotyping in constitutional cytogenetic testing, the technology is also beginning to displace conventional methods for the clinical diagnosis of hematological cancers, according to a report by researchers from several European

Researchers from Radboud University Nijmegen Medical Center have published a method of non-invasive prenatal diagnosis using massively parallel sequencing-by-ligation on the Life Technologies SOLiD 4 platform.

Researchers from the Netherlands who used exome sequencing in parent-child trios found mutations in children with unexplained mental retardation that were not present in either parent.

Decode is hoping to incorporate the recently discovered SNP on chromosome 4p16 into a multi-gene panel test for UBC, according to Decode's Kari Stefansson.

Techgene, a three-year project that is funded under the European Union's 7th Framework Program, involves 12 groups from nine European countries and is in the midst of testing several second-generation sequencing platforms for diagnosing genetic diseases.

Several European lab directors interviewed by BioArray News said the switch occurred over the past year as a result of falling array prices and because lab techs have become more confident in their ability to interpret results as they have gained more experience with the technology.

The arrangement will take advantage of InteRNA's proprietary lentiviral-based miRNA over-expression library, according to the partners.

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The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.