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Radboud University Medical Centre

Exome sequences from thousands of parent-child trios led to 10 new genes in which de novo mutations are over-represented in individuals with intellectual disability. 

The firm's SelectMDx prostate cancer test will be used in conjunction with MRI to evaluate their combined effectiveness in nominating patients for prostate biopsy.

Through exome and targeted sequencing, researchers identified de novo mutations in at least two genes involved in a condition called Möbius syndrome.

The study identified five SNPs significantly associated with five-year progression-free survival and defined risk groups with widely different risks of disease recurrence.

After further validation, Thermo Fisher commercially launched a CE-IVD version of the same panel last month.

NEW YORK (GenomeWeb) – The Netherlands is in the midst of a nationwide study of noninvasive prenatal testing to provide it with the scientific data needed to help decide whether and how to implement the test as part of the country's prenatal screening program.

NEW YORK (GenomeWeb News) – A new study in the New England Journal of Medicine is underscoring the importance of de novo mutations in non-syndromic intellectual disability, while highlighting the potential of using exome sequencing to diagnose severe intellectual disability case

Researchers at the Radboud University Nijmegen Medical Center are looking at ways to expand their diagnostic exome sequencing program for a range of diseases, even as they go through data from the pilot phase of the effort.

Alnylam Pharmaceuticals last week published preclinical data describing the development of a dendritic cell cancer vaccine enhanced with RNAi.

This story was published on June 28.

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The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.

In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.

MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.

In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.