Queen Mary University of London
Gene Expression, Histology Reveal Clues for Targeted Rheumatoid Arthritis Treatment
Histological profiling and RNA sequencing helped identify synovial biopsy features for predicting targeted biologic therapy response in rheumatoid arthritis.
Whole-Genome Sequencing Can Diagnose Neurological Repeat Expansion Disorders, UK Study Finds
The study involved researchers from Queen Mary University of London, University College London, Illumina, and Genomics England and NHS England.
Exagen, QMUL to Develop Molecular Signatures for Rheumatoid Arthritis Therapy Selection
The assays under development will segment patients according to gene expression in their synovial tissue biopsies to personalize therapy selection.
Benign Hypertension-Causing Tumors Linked to Somatic Codriver Mutations
Researchers identified a double-mutant form of hypertension-causing adrenal gland tumors that appear to form in response to hormone spikes during pregnancy, puberty, or menopause.
Study investigators found that patients with ctDNA-positive results after surgery were at higher risk of bladder cancer recurrence than those who were ctDNA-negative.