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In Nature this week: holistic allele-specific tumor copy number heterogeneity (HATCHet) approach to infer allele- and clone-specific copy-number aberrations and whole-genome duplications, and more.

A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.

A new analysis finds that Neanderthal ancestry can be found across human populations, including among Africans.

Researchers used a statistical approach to identify Neanderthal ancestry in thousands of individuals, refining estimates on the proportion of ancestry in various human populations.

In PNAS this week: metatranscriptomic analyses of soil viruses, links between endogenous retroviruses and memory impairment in fruit flies, and more.

In PNAS this week: analysis of extensively drug-resistant Mycobacterium tuberculosis strain, regulation of obesity-linked gene, and more.

With deep learning, researchers profiled de novo noncoding variants in individuals with ASD from nearly 1,800 families, identifying regulatory factors and related pathways.

Researchers have uncovered red wolf genes within a population of wild dogs living in Texas, according to Gizmodo.

In Science this week: series of reviews about gene modification, and more.

Diet- and height-related variants were selected for in a Flores Island pygmy population, according to a study, which also provided insights into the population's history.

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Springer Nature announces €9,500 fee to make papers open-access in Nature and its family of journals.

Librarians have concluded that notebooks that belonged to Charles Darwin that were thought to have been lost were actually likely stolen, CNN reports.

An early SARS-CoV-2 alteration may have enabled it to spread more easily, according to the New York Times.

In PNAS this week: ultrarare variants contribute to aging-related hearing loss, telomeres of cells infected with herpesvirus, and more.