Princeton
Broad Institute, Collaborators Eye CRISPR Panel to Detect SARS-CoV-2 Variants, Respiratory Viruses
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The group has developed a panel to detect SARS-CoV-2, other coronaviruses, and influenza A and B that also identified and differentiated six variant lineages.
Psychiatric Disorder Risk Affected by Dysregulation of RNA-Binding Proteins
Using a deep learning approach to study mutations in target sites of RNA-binding proteins, researchers identified DDHD2 as a candidate schizophrenia risk gene.
Microbiome Metabolite Screening Method Uncovers Gut Microbe-Drug Interactions, Variability
A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.
Neanderthal Genetic Ancestry Found in Present-Day African Populations
Researchers used a statistical approach to identify Neanderthal ancestry in thousands of individuals, refining estimates on the proportion of ancestry in various human populations.
Autism Whole-Genome Analysis Reveals Regulatory Consequences of Noncoding Variants
With deep learning, researchers profiled de novo noncoding variants in individuals with ASD from nearly 1,800 families, identifying regulatory factors and related pathways.