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Princess Margaret Hospital

Princess Margaret Cancer Centre, Inivata Partner on Clinical Liquid Biopsy Studies

Inivata's InVisionFirst-Lung and RaDaR assays will support studies of the use of liquid biopsies in early and minimal residual disease detection.

Princess Margaret Researchers Improve HPV Detection in Blood With NGS Method
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The method, called HPV-Seq, detected ctDNA with high sensitivity and specificity, and could help hone precision treatments of HPV-related cancers.

Liquid Biopsy Startup Adela Launches With $60M Series A Financing Round

The Toronto-based company will use the funding to commercialize its cell-free DNA methylation sequencing technology as an early cancer detection test.

Researchers Aim to Improve Lynch Syndrome Testing With Genetic-Epigenetic Combination Method
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The sequencing test involves a single library preparation that is then split for parallel analysis of promoter methylation, MSI calculation, and gene mutation detection.

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
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At the ASHG 2020 virtual meeting, researchers presented data showing they could use the method to enrich for placental DNA in maternal plasma samples.

Jun 26, 2020

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method
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Oct 7, 2019

Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline

Feb 7, 2019

Cancer-Associated Circular RNAs Catalogued Across Tumor Types

Feb 4, 2019

Genome Canada, Partners Award $42.6M in Genomics, Informatics Research Funding

Nov 21, 2018

Immunoprecipitation Method Could Improve Epigenetic Early Cancer Detection Tests
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Nov 14, 2018

Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies

Nov 5, 2018

Metastatic Breast Cancer Clinical Trial Forged by Epic Sciences, Canadian Consortium

Nov 1, 2017

Study Highlights Molecular Changes in Tumor-Neighboring Tissue in Breast Cancer Patients

Oct 24, 2017

Cancer Drug Response Linked to Transcript Isoform Markers

Oct 5, 2017

Ontario OCTANE Genomic Data-Sharing Study Kicks Into Gear
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Aug 4, 2017

Brain Tumors in Childhood Cancer Survivors Reveal Radiation-Induced Mutations

May 25, 2017

Ontario Institute for Cancer Research Launches Translational Research Programs

May 11, 2017

Multiple Myeloma Study Suggests Circulating DNA Test Complements Bone Marrow Testing

Jan 9, 2017

Aggressive Prostate Cancer Harbors Genomic Patterns

Dec 7, 2016

Signature of 17 Genes Could Predict Prognosis in AML Patients

Nov 23, 2016

Few Cancer Patients With Tumor Profiles Enter Genotype-Matched Trials, But Response Rate is Higher

May 13, 2016

Colorectal Cancer Patients' Cetuximab Response Can Be Discerned From FCGR2A Genotype
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Nov 6, 2015

AACR Launches International Genomic, Clinical Data Sharing Project for Cancer

Nov 17, 2014

SickKids, UHN Pilot New Cloud Infrastructure for Healthcare

Jun 6, 2012

Survey of Canadian Cancer Patients Reveals Their Willingness to Pay for PGx Tests
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Breaking News
The Scan

Looking for Omicron

NPR reports that SARS-CoV-2 testing in the US has gotten better but also that some experts say more needs to be done to better track the Omicron variant.

Holmes Alleges Abuse

The Associated Press reports that Theranos' Elizabeth Holmes has testified at her wire fraud trial that her business and romantic partner abused her.

Bit More Diverse, But More to Do

While Black and Hispanic patients are more likely to participate in cancer clinical trials than previously, they are still underrepresented, according to US News & World Report.

PNAS Papers on Yeast Gene Silencing, Zika Virus Inhibition, Immunoglobulin Hypermutation

In PNAS this week: gene silencing in Saccharomyces cerevisiae, possible neuroprotective role for SHFL in a mouse model of Zika virus infection, and more.