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Princess Margaret Hospital

Cancer Early Detection Shows Promise in New Li-Fraumeni Syndrome Data
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Researchers are advancing a multiomic method they hope can improve care for patients who have inherited a dramatic risk of developing cancer.

Early Cancer Detection in Li-Fraumeni Syndrome Patients Enabled by Liquid Biopsy Test

Integrated analysis of cell-free DNA appears to help predict the development of cancer in individuals with the hereditary cancer susceptibility condition.

Princess Margaret Cancer Centre, Inivata Partner on Clinical Liquid Biopsy Studies

Inivata's InVisionFirst-Lung and RaDaR assays will support studies of the use of liquid biopsies in early and minimal residual disease detection.

Princess Margaret Researchers Improve HPV Detection in Blood With NGS Method
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The method, called HPV-Seq, detected ctDNA with high sensitivity and specificity, and could help hone precision treatments of HPV-related cancers.

Liquid Biopsy Startup Adela Launches With $60M Series A Financing Round

The Toronto-based company will use the funding to commercialize its cell-free DNA methylation sequencing technology as an early cancer detection test.

Feb 19, 2021

Researchers Aim to Improve Lynch Syndrome Testing With Genetic-Epigenetic Combination Method
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Nov 2, 2020

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
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Jun 26, 2020

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method
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Oct 7, 2019

Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline

Feb 7, 2019

Cancer-Associated Circular RNAs Catalogued Across Tumor Types

Feb 4, 2019

Genome Canada, Partners Award $42.6M in Genomics, Informatics Research Funding

Nov 21, 2018

Immunoprecipitation Method Could Improve Epigenetic Early Cancer Detection Tests
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Nov 14, 2018

Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies

Nov 5, 2018

Metastatic Breast Cancer Clinical Trial Forged by Epic Sciences, Canadian Consortium

Nov 1, 2017

Study Highlights Molecular Changes in Tumor-Neighboring Tissue in Breast Cancer Patients

Oct 24, 2017

Cancer Drug Response Linked to Transcript Isoform Markers

Oct 5, 2017

Ontario OCTANE Genomic Data-Sharing Study Kicks Into Gear
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Aug 4, 2017

Brain Tumors in Childhood Cancer Survivors Reveal Radiation-Induced Mutations

May 25, 2017

Ontario Institute for Cancer Research Launches Translational Research Programs

May 11, 2017

Multiple Myeloma Study Suggests Circulating DNA Test Complements Bone Marrow Testing

Jan 9, 2017

Aggressive Prostate Cancer Harbors Genomic Patterns

Dec 7, 2016

Signature of 17 Genes Could Predict Prognosis in AML Patients

Nov 23, 2016

Few Cancer Patients With Tumor Profiles Enter Genotype-Matched Trials, But Response Rate is Higher

May 13, 2016

Colorectal Cancer Patients' Cetuximab Response Can Be Discerned From FCGR2A Genotype
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Nov 6, 2015

AACR Launches International Genomic, Clinical Data Sharing Project for Cancer

Breaking News
The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.