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Princess Margaret Hospital

Liquid Biopsy Startup Adela Launches With $60M Series A Financing Round

The Toronto-based company will use the funding to commercialize its cell-free DNA methylation sequencing technology as an early cancer detection test.

Researchers Aim to Improve Lynch Syndrome Testing With Genetic-Epigenetic Combination Method
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The sequencing test involves a single library preparation that is then split for parallel analysis of promoter methylation, MSI calculation, and gene mutation detection.

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
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At the ASHG 2020 virtual meeting, researchers presented data showing they could use the method to enrich for placental DNA in maternal plasma samples.

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method
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Investigators reported that methylation profiling could distinguish brain cancer subtypes and could detect kidney cancer with striking sensitivity in early experiments.

Prostate Cancer Methylation Levels Linked to Regulatory Variants in Germline

Researchers identified variants in the germline that appear to influence DNA methylation levels in prostate cancer tumors or in precancerous tissues.

Feb 7, 2019

Cancer-Associated Circular RNAs Catalogued Across Tumor Types

Feb 4, 2019

Genome Canada, Partners Award $42.6M in Genomics, Informatics Research Funding

Nov 21, 2018

Immunoprecipitation Method Could Improve Epigenetic Early Cancer Detection Tests
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Nov 14, 2018

Methylation-Based Cancer Early Detection Method Shows Promise in Preliminary Studies

Nov 5, 2018

Metastatic Breast Cancer Clinical Trial Forged by Epic Sciences, Canadian Consortium

Nov 1, 2017

Study Highlights Molecular Changes in Tumor-Neighboring Tissue in Breast Cancer Patients

Oct 24, 2017

Cancer Drug Response Linked to Transcript Isoform Markers

Oct 5, 2017

Ontario OCTANE Genomic Data-Sharing Study Kicks Into Gear
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Aug 4, 2017

Brain Tumors in Childhood Cancer Survivors Reveal Radiation-Induced Mutations

May 25, 2017

Ontario Institute for Cancer Research Launches Translational Research Programs

May 11, 2017

Multiple Myeloma Study Suggests Circulating DNA Test Complements Bone Marrow Testing

Jan 9, 2017

Aggressive Prostate Cancer Harbors Genomic Patterns

Dec 7, 2016

Signature of 17 Genes Could Predict Prognosis in AML Patients

Nov 23, 2016

Few Cancer Patients With Tumor Profiles Enter Genotype-Matched Trials, But Response Rate is Higher

May 13, 2016

Colorectal Cancer Patients' Cetuximab Response Can Be Discerned From FCGR2A Genotype
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Nov 6, 2015

AACR Launches International Genomic, Clinical Data Sharing Project for Cancer

Nov 17, 2014

SickKids, UHN Pilot New Cloud Infrastructure for Healthcare

Jun 6, 2012

Survey of Canadian Cancer Patients Reveals Their Willingness to Pay for PGx Tests
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Apr 12, 2012

Princess Margaret Foundation Seeks $1B for Personalized Cancer Programs

Aug 3, 2011

In Pilot Study, OICR Aims to Validate PacBio RS for Targeted Sequencing of Cancer Patients
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Breaking News
The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.