Princess Margaret Hospital
Multimodal Cell-Free DNA Test May Help Detect Cancer Early in Li-Fraumeni Syndrome Patients
Researchers analyzed cfDNA from blood focusing on genomic, fragmentomic, and epigenomic features linked to cancer in individuals with germline TP53 mutations.
Lung Cancer Study Suggests Liquid Biopsy Reduces Treatment Delays, Boosts Target Detection
A clinical trial suggests circulating tumor DNA genotyping prior to tissue-based diagnoses can reduce time to treatment in advanced NSCLC patients.
Personalized Residual Disease Assays Show Promise to Overcome Liquid Biopsy Challenges in Sarcomas
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New data presented at the ASCO annual meeting this week showed that tumor-informed assays could detect emerging recurrence ahead of imaging.
Early-Phase Immunotherapy Trial Results Lend Further Support for ctDNA as Surrogate Endpoint
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Researchers from Princess Margaret Cancer Center demonstrated that a decrease in ctDNA within four weeks after immunotherapy treatment was associated with response and survival.
Researchers are advancing a multiomic method they hope can improve care for patients who have inherited a dramatic risk of developing cancer.