Researchers used exome capture RNA sequencing to come up with a collection of circRNAs in dozens of cancer types, including proposed prostate cancer markers.
In Genome Research this week: transcriptomic profiles of centenarians, role for PRDM9 expression in various tumor types, and more.
In Genome Biology this week: genome sequencing study of a wild cherry tree, transcriptomic analysis of a planarian model organism, and more.
Researchers found that air pollution levels affected the expression of genes linked to cardio-metabolic and respiratory traits more than genetic ancestry.
Expression and copy number profiles from histologically normal duct tissue near tumors suggest a "field of cancerization" may exist in epithelial cells around cancer.
In Nucleic Acids Research this week: disease network resource, database of epigenetic consequences of de novo mutations, and more.
Using genomic data from large cancer cell line collections, investigators identified versions of spliced genes that spell better or worse drug response.
Called GA4GH Connect, it calls on the alliance's 500-plus members to develop new data sharing standards for use in major international genomic data initiatives.
The software, developed by researchers at the Ontario Institute for Cancer Research, uses machine learning methods to classify mutations as germline or somatic.
The initiatives are being funded with C$24 million over two years and will focus on acute leukemia, immuno-oncology, and brain, ovarian, and pancreatic cancer.
The US National Institutes of Health's All of Us project awarded $4.6 million to the company Color to develop a genetic counseling resource for the program.
The Times of India reports on a pilot study that used genomic testing to determine whether patients had drug-resistant tuberculosis.
New guidelines say that more women may benefit from genetic testing for hereditary breast or ovarian cancer, according to the Los Angeles Times.
In Cell this week: small proteins identified among human microbiome, role for tumor microbes in pancreatic cancer survival, and more.