OHSU Cancer Centers Nudge Oncologists Toward DPYD Testing as PGx Supporters Push For Guidelines Change Premium Several institutions, swayed by PGx experts and advocates, are setting up DPYD testing to avoid deadly chemo toxicities in patients even though the NCCN and FDA don't back it. Scale Biosciences, Still in Stealth Mode, to Develop Single-Cell, Spatial Biology Tech Premium UW professor Jay Shendure and ex-Illumina R&D maven Frank Steemers have teamed up to commercialize combinatorial indexing-based sequencing assays. NanoString Technologies, OHSU Partner on Breast Cancer Spatial Protein Profiling Assay Development A new GeoMx Digital Spatial Profiler assay will have up to 30 protein targets and will be validated for potential use as a laboratory-developed test. Dozens of Introduction Events Sparked SARS-CoV-2 Spread in Oregon, Sequence Data Suggests Premium At the ASHG conference, a researcher described efforts to sequence SARS-CoV-2 genomes from Oregon to investigate introductions, super-spreader events, and viral biology. Ymir Genomics Licenses Urine Biomarkers for Liver Disease Detection From OHSU Ymir Genomics and OHSU will share in any value created by the biomarkers and will jointly publish and validate the biomarkers in a large-scale multi-center study. May 12, 2020 New Methods Draw Single-Cell, Spatial Genomics Data Closer Together Premium Feb 20, 2020 Radiation-Boosted Liquid Biopsy Shows Promise in Early-Stage Lung Cancer Premium Jan 13, 2020 Taproot's Master Observational Trial Attempting to Gather Missing Outcomes Data in Precision Oncology Premium Jan 2, 2020 Taproot Health, Five Cancer Centers Agree to Conduct Precision Oncology Master Trial, Share Data May 7, 2019 Kiyatec Targeting Clinical Oncology Space With 3D Cell Culture Technology Premium Jan 10, 2019 Bioinformatics Startup Looks to Break Data Silos for Precision Medicine Premium Oct 17, 2018 Acute Myeloid Leukemia Analysis Brings Together Integrated Omic, Drug Response Profiles May 11, 2018 Genome Sequencing Increases Sensitivity of Preconception Carrier Screens, CSER Study Finds Nov 14, 2017 Ymir Genomics, OHSU Knight Cancer Institute Collaborate to Develop HCC Biomarkers Sep 28, 2017 Biological Dynamics Signs Tech Access Deal With OHSU Aug 2, 2017 Gene Editing Used to Repair Inherited Mutation in Embryos May 26, 2017 OHSU Knight Cancer Institute Wins $9.2M NCI Grant Apr 3, 2017 Biocept, OHSU Reach Deal on Liquid Biopsy Nov 10, 2016 NanoString, OHSU Partner on Myeloid Gene Expression Panels Oct 24, 2016 Precision Medicine Master Trial Aims to Tailor Therapy for Acute Myeloid Leukemia Patients Premium Sep 21, 2016 Global Ocean Virus Genome Collection Sheds Light on Ecosystem Apr 4, 2016 Intel-OHSU Data Sharing Cloud to Include Pilot Projects in Prostate, Other Cancers Premium Mar 31, 2016 Dana-Farber, OICR Join OSHU-led Cancer Data Sharing Effort Feb 9, 2016 Immunovia Partners With Mount Sinai to Validate Pancreatic Cancer Blood Test Oct 5, 2015 OHSU, Immunovia Collaborate on Test for Early Detection of Pancreatic Cancer Load More Breaking News Mainz Biomed to Initiate Pivotal US Clinical Study for Colorectal Cancer Early Detection Test Pacific Biosciences, Boston Children's Hospital to Collaborate on Rare Disease Variant Pilot Project Caris Life Sciences, Hummingbird Bioscience Partner on Anti-HER3 Therapy Advancement Gut Microbiome Characteristics Tied to Depressive Symptoms in New Studies Bluestar Genomics to Study Pancreatic Cancer Early Detection Test in Type 2 Diabetes Patients The Scan Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan. Lupus Heterogeneity Highlighted With Single-Cell Transcriptomes Using single-cell RNA sequencing, researchers in Nature Communications tracked down immune and non-immune cell differences between discoid lupus erythematosus and systemic lupus erythematosus. Rare Disease Clues Gleaned From Mobile Element Insertions in Exome Sequences With an approach called MELT, researchers in the European Journal of Human Genetics uncovered mobile element insertions in exomes from 3,232 individuals with or without developmental or neurological abnormalities. Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.