Ohio State FDA Grants EUAs for Coronavirus Tests from 3B Blackbio, Ohio State, and Others The tests are designed to detect regions in the SARS-CoV-2 genome in respiratory samples or antibodies against the virus in human serum, plasma, or blood. Case Study Highlights Potential of Autopsies to Study Strengths, Limitations of Liquid Biopsy Premium Investigators are building upon an initial case study that allowed them to assess how well ctDNA captured a cancer's full genomic heterogeneity compared to tissue biopsies. Nanopore Sequencing-Based Mapping Methods Reveal Open Chromatin, Methylation Patterns Premium All three methods build on the use of methyltransferases to mark accessible regions of the genome, using nanopore sequencing to detect the modifications. DoE Awards $64M in Funding to Groups Using Genomics to Study Plants, Microbes The projects are focused on the impact of microbe communities on soil nutrient cycling, and the relationship between gene function and beneficial plant traits. Synthetic CRISPR Inhibitors Suppress DNA Breaks Induced by Cas12a Ohio State University researchers found that a phosphorothioate-modified DNA-crRNA duplex completely blocked the function of Cas12a. Dec 14, 2018 In Brief This Week: Cancer Research UK, NeoGenomics, Luminex, and More Jun 28, 2018 MGMT Promoter Methylation Predicts Survival of Glioma Patients Following Combination Treatment Mar 29, 2018 Study Supports Sequencing for Lynch Syndrome Diagnoses in CRC Patients Oct 25, 2017 OSU Researchers Advancing Next-Gen Sequencing Test for Detecting Microsatellite Instability Premium Oct 24, 2016 Precision Medicine Master Trial Aims to Tailor Therapy for Acute Myeloid Leukemia Patients Premium Sep 12, 2016 HudsonAlpha to Provide Sequencing Services for ORIEN Cancer Initiative Sep 22, 2015 OSU Awarded $12.4M Grant to Study Genetics of Dilated Cardiomyopathy Aug 27, 2015 OSU Group Launches CanDL to Match Somatic Mutations With Therapy, Clinical Trials Premium Apr 9, 2015 Ohio State Scaling up Precision Cancer Medicine Trial as It Aims to Stratify Patients Premium Jan 15, 2015 OSU Study Uses MAKER Pipeline to ID Genetic Markers for Phylogenetic Studies in Plant Genus Premium Oct 14, 2014 IP Roundup: Affymetrix, Nabsys, Ohio State U, Fujirebio Win US Patents Premium Aug 12, 2014 Compact Antarctic Midge Genome Offers Clues to Extreme Adaptation Feb 26, 2014 Researchers Outline Strategy to ID Potential New Lung Cancer Mutation in Super-Responder Premium Oct 8, 2013 Life Tech Certifies 11 Additional Labs to Provide Ion Proton Exome Sequencing Services Sep 26, 2013 Microlin Bio Licenses miRNA Patents from Ohio State May 2, 2013 TCGA Data Yields miRNA/mRNA Signature with Promise as Breast Cancer Prognostic Premium Mar 14, 2013 OSU Team Links microRNA to ‘Clock’ that Controls Embryonic Tissue Segmentation Premium Jan 10, 2013 OSU Researcher Sanctioned for Falsifying microRNA Data Premium Jul 26, 2012 JCI Studies Uncover Metabolic, Tumor-Suppressive Roles for miR-122 in the Liver Premium Jul 12, 2012 OSU Team Reports on Link between Secreted microRNAs and Pro-Metastatic Inflammatory Response Premium Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.