Ohio State FDA Grants EUAs for Coronavirus Tests from 3B Blackbio, Ohio State, and Others The tests are designed to detect regions in the SARS-CoV-2 genome in respiratory samples or antibodies against the virus in human serum, plasma, or blood. Case Study Highlights Potential of Autopsies to Study Strengths, Limitations of Liquid Biopsy Premium Investigators are building upon an initial case study that allowed them to assess how well ctDNA captured a cancer's full genomic heterogeneity compared to tissue biopsies. Nanopore Sequencing-Based Mapping Methods Reveal Open Chromatin, Methylation Patterns Premium All three methods build on the use of methyltransferases to mark accessible regions of the genome, using nanopore sequencing to detect the modifications. DoE Awards $64M in Funding to Groups Using Genomics to Study Plants, Microbes The projects are focused on the impact of microbe communities on soil nutrient cycling, and the relationship between gene function and beneficial plant traits. Synthetic CRISPR Inhibitors Suppress DNA Breaks Induced by Cas12a Ohio State University researchers found that a phosphorothioate-modified DNA-crRNA duplex completely blocked the function of Cas12a. Dec 14, 2018 In Brief This Week: Cancer Research UK, NeoGenomics, Luminex, and More Jun 28, 2018 MGMT Promoter Methylation Predicts Survival of Glioma Patients Following Combination Treatment Mar 29, 2018 Study Supports Sequencing for Lynch Syndrome Diagnoses in CRC Patients Oct 25, 2017 OSU Researchers Advancing Next-Gen Sequencing Test for Detecting Microsatellite Instability Premium Oct 24, 2016 Precision Medicine Master Trial Aims to Tailor Therapy for Acute Myeloid Leukemia Patients Premium Sep 12, 2016 HudsonAlpha to Provide Sequencing Services for ORIEN Cancer Initiative Sep 22, 2015 OSU Awarded $12.4M Grant to Study Genetics of Dilated Cardiomyopathy Aug 27, 2015 OSU Group Launches CanDL to Match Somatic Mutations With Therapy, Clinical Trials Premium Apr 9, 2015 Ohio State Scaling up Precision Cancer Medicine Trial as It Aims to Stratify Patients Premium Jan 15, 2015 OSU Study Uses MAKER Pipeline to ID Genetic Markers for Phylogenetic Studies in Plant Genus Premium Oct 14, 2014 IP Roundup: Affymetrix, Nabsys, Ohio State U, Fujirebio Win US Patents Premium Aug 12, 2014 Compact Antarctic Midge Genome Offers Clues to Extreme Adaptation Feb 26, 2014 Researchers Outline Strategy to ID Potential New Lung Cancer Mutation in Super-Responder Premium Oct 8, 2013 Life Tech Certifies 11 Additional Labs to Provide Ion Proton Exome Sequencing Services Sep 26, 2013 Microlin Bio Licenses miRNA Patents from Ohio State May 2, 2013 TCGA Data Yields miRNA/mRNA Signature with Promise as Breast Cancer Prognostic Premium Mar 14, 2013 OSU Team Links microRNA to ‘Clock’ that Controls Embryonic Tissue Segmentation Premium Jan 10, 2013 OSU Researcher Sanctioned for Falsifying microRNA Data Premium Jul 26, 2012 JCI Studies Uncover Metabolic, Tumor-Suppressive Roles for miR-122 in the Liver Premium Jul 12, 2012 OSU Team Reports on Link between Secreted microRNAs and Pro-Metastatic Inflammatory Response Premium Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.