Office of Public Health Genomics

Despite a massive budget shortfall, Office of Public Health Genomics Director Muin Khoury will continue to press for government policies and initiatives that promote safe and effective genomic medicine products from a public health perspective.

The "magnitude of net health benefit" from use of eight marketed tests analyzing 58 variants and 29 genes reviewed by the Evaluation of Genomic Applications in Practice and Prevention Working Group is "negligible," the expert panel wrote in a statement.

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Allen Roses, Muin Khoury, Mary Relling, Martin Godbout

"The promise of genomics in the practice of medicine is great and exciting, but today the use of personal genomic tests is still not ready for prime time," a CDC official said in a video address to doctors and the general public.

The CDC's Muin Khoury is disappointed in the paucity of genomics-related prevention and education objectives that have been proposed as part of the US federal government's Healthy People 2020 project.

The director of CDC's Office of Public Health Genomics detailed GAPPNet's plans to close the hole in translational research and discussed how "the stars are aligning" in healthcare reform to further drive the integration of genomics and personalized medicine into clinical practice.

The industry standards issued last December by 23andMe, Decode, and Navigenics are "a good start, but they are really not where they need to be," said Muin Khoury, director of the CDC's Office of Public Health Genomics.

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.