NYU
Xenotransplant Responses, Interactions Unraveled With Multiomic Analyses
Researchers tracked molecular consequences of transplanting genetically modified pig hearts into two brain-dead recipients, identifying distinct effects in each.
The lab achieved a sequencing quality score of Q140, or one error in a 100 trillion bases, for detecting single-base substitutions on single strands of DNA.
Tail Loss in Humans, Apes Linked to Transposable Element Impacting Splicing
Investigators found interacting Alu element insertions that influenced TBXT transcription factor splicing, leading to tail loss and higher risk for neural tube defects.
Synthetic Yeast Chromosome Progress Presented in New Publications
In multiple papers, members of the Synthetic Yeast Project consortium known as Sc2.0 described progress in producing and studying synthetic yeast chromosomes and strains.
NCI Grants to Fund Myeloid Leukemia Research at Ohio State, NYU
The research teams will use multiomic approaches to better stratify patient risk through ancestry-adjusted genetics and uncover drivers of inflammation in AML.