A new study in Science used allele-specific expression data to find candidate genes that may have contributed to mendelian muscle disease in patients.
The method allows for the annotation of cells by their genotype and capture of single-cell transcriptomes, even when the cells aren't morphologically distinct.
A New York Genome Consortium-led team plans retrospective and prospective analyses on very rare cancers in the hopes of improving treatment options available for patients.
The grant is part of a CZI effort to fund research projects supporting the Human Cell Atlas, which is building a reference atlas of all human cell types.
The five-year gift will support the building and maintenance of the NYGC's genomics infrastructure to work with its institutional founding members.
With DNA methylation data for more than 1,800 chronic lymphocytic leukemia B cells, researchers tracked CLL epimutation rates and saw lineages with distinct treatment responses.
Gencove offers low-coverage whole-genome sequencing and has developed imputation algorithms and informatics to extract useful information from the data.
The method builds on a previous technique the group developed to measure transcriptomes and surface proteins from single cells.
The researchers uncovered disease-linked genes that are expressed in certain cells and disease stages and discovered various gene expression modules.
ScienceInsider reports that rude and unprofessional paper reviewers are common and can have harmful effects.
The US Senate has confirmed Stephen Hahn as the next commissioner of the Food and Drug Administration, according to the New York Times.
CNBC reports Apple is partnering with Color Genomics to offer its employees free DNA screening for disease.
In Science this week: researchers use CRISPR tool to find gut microbiome molecules involved in immunity, and more.