Northwestern University Proteomics Researchers Aim to Improve Analyses of Peptide-Level Data Premium The aim is to improve the accuracy of the protein measurements commonly reported as the output of proteomic experiments and uncover obscured biological signals. Lurie Children's Hospital Details Migration of Clinical Diagnostics Lab to hg38 Reference Genome Premium At the AMP 2020 annual meeting, the Chicago pediatric hospital described how to modernize variant calling, as new human genome assemblies are in the works. Demand Grows for Chief Research Information Officers as Role Evolves Along With Data Types Premium CRIOs and their equivalents often are asked to bridge academic and provider sides of institutions to support clinical trials and data analytics with massive research datasets. Autism Subtype Marked by Abnormal Lipid Levels Uncovered in Analysis of Research, Healthcare Data An analysis of whole-exome sequencing, brain gene expression, and health data suggests an autism subtype marked by dyslipidemia. Incidental Findings Most Frequent in Cancer Risk Genes, EMERGE III Data Show Researchers identified secondary or incidental findings in just over 3 percent of the nearly 22,000 EMERGE III participants, who were profiled with a 109-gene panel. Feb 18, 2020 Polygenic Risk Score Studies Suggest Conventional Heart Disease Prediction Methods Still Preferable Nov 11, 2019 Chatbots Could Help Human Genetic Counselors Focus on Patient Concerns Aug 15, 2019 Actionable Mutation Analysis Reveals Germline Risk in Older CRC Patients Apr 30, 2019 PCOS Traits Tied to Rare Variants in Testosterone-Related Gene Feb 11, 2019 Glioblastoma Markers of Checkpoint Immunotherapy Response Discovered Nov 9, 2018 National Cancer Institute Awards $4M to Brain Tumor Sequencing Projects Oct 23, 2018 Warfarin Bleeding Risk SNPs Identified in African Americans Jul 25, 2018 Sleep, Depression Appear to Involve Shared Gene Networks Mar 29, 2018 Researchers Develop Web App to Improve Curation, Delivery of Genomic Knowledge to Point of Care Premium Dec 1, 2017 Kidney Transplant Tolerance Signatures Provide Clues to Curbing Excess Immunosuppression Nov 15, 2017 Rare Mutation Found Among Amish Population Protects Against Some Effects of Aging Nov 1, 2017 NIH Awards Grants Supporting Social Epigenomics Research Jul 31, 2017 Genetic Testing Evaluated For Diagnosing Epilepsy, Monogenic Conditions Dec 22, 2016 Gene Expression Signature for Systemic Sclerosis May Yield Diagnostic Tool Nov 16, 2016 Northwestern University to Use Guardant Liquid Biopsy for Patient Testing Sep 6, 2016 Prostate Cancer Grades Can Be Distinguished Using MicroRNA Signature, Study Finds Sep 4, 2015 Northwestern's Kelleher Awarded $7.5M Grant to Advance Top-Down Proteomics Premium Jun 30, 2015 Picking up Protease Allowed Y. Pestis to Cause Pneumonic Plague, Study Finds Apr 29, 2015 Mitochondrial Sequences From Indigenous Alaskans Offer Clues to Past Arctic Migrations Apr 10, 2015 Northwestern Team Develops System for Simplifying Sample Cleanup in Top-Down Proteomics Premium Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.