Northwestern University
Vegetarian Diet GWAS Leads to Related Genetic Loci, Genes
Researchers used UK Biobank data to track down genetic variants with significant or tenuous ties to vegetarianism, along with related brain- or lipid metabolism-related genes.
DNA Methylation Study Finds Association Between Biological Aging, Adverse Childhood Experiences
The findings show that people who experienced adverse childhood experiences such as negligence or violence have accelerated biological aging later in life.
Coronary Artery Calcium Score Beats Polygenic Risk Score at Heart Disease Risk Prediction
The combination of the two scores also had no additive predictive power compared with the coronary artery calcium score alone, the researchers found.
Acute Myeloid Leukemia 3D Genome Analysis Uncovers Subtype-Specific Changes
Along with enhancer and silencer alterations, researchers identified AML-related methylation and regulation changes that correspond to genome organization shifts.
Five research groups participating in the NHGRI-funded Molecular Phenotypes of Null Alleles in Cells initiative aim to characterize 1,000 null alleles in a pilot phase.