NIST To Q40 and Beyond: Sequencing's Accuracy Revolution is Happening Now Premium New, more accurate methods are posing problems for the NGS ecosystem as researchers rethink the concept of accuracy altogether. NIST Analysis Discovers Sample Processing Bias in Metagenomic Wastewater Surveillance Premium The finding underscores the need to standardize sampling protocols to minimize biases in wastewater antimicrobial resistance monitoring. MDIC Launches Initiative to Improve Accuracy of Next-Generation Sequencing-Based Cancer Diagnostics As part of the initiative, MDIC will manufacture, validate, and distribute reference samples to support the validation of NGS-based cancer diagnostics. New Products Posted to GenomeWeb: MGI, Illumina, NIST, More New products posted to GenomeWeb for the week of July 25, 2022. Genome in a Bottle Consortium Releases Benchmark Data for Challenging Medically Relevant Genes Premium The public-private consortium added benchmarking data for 273 difficult-to-analyze but medically important genes previously omitted in its reference. Oct 16, 2020 Interdisciplinary NIST Team Claims qPCR Improvements Using Unusual Math Tweaks Premium Sep 11, 2020 NIST Creating Reference Material for SARS-CoV-2 Diagnostic Assay Developers Premium Aug 14, 2020 New Products Posted to GenomeWeb: Centogene, NIST, GeneDx Jul 10, 2020 New Products Posted to GenomeWeb: Illumina, NIST, Horizon Discovery, More Jun 15, 2020 Genome In a Bottle Consortium Releases Structural Variant Calling Benchmark Data Premium Jan 21, 2020 FNIH Team Selects Cancer Biomarkers in Phase I of Liquid Biopsy Reference Standards Project Premium May 24, 2019 Multi-Site Study Tests Power of Commercial Reference Materials in Comparing Liquid Biopsy Assays Premium Mar 12, 2019 GA4GH Benchmarking Team Releases Best Practices for Comparing Germline Variant Calls Mar 8, 2017 NIST, ATCC Develop STR-Based Method to Identify Contamination of Mouse Cell Lines Premium Oct 18, 2016 Genome In A Bottle Consortium Developing New Reference Materials, Variant Call Sets Premium Oct 11, 2016 NIST Team Explores Alternative to Graphene for Nanopore Sequencing Premium Jul 19, 2016 ATCC Inks Validation Deal With NIST for Mouse Cell Line Verification Jul 14, 2016 SeraCare, NIST Partner on CtDNA Reference Standards for Dx Mar 2, 2016 NIST, Stanford Study Underscores Need for Sequencing Standards Feb 25, 2016 White House Announces Efforts to Accelerate Precision Medicine Initiative Jan 21, 2016 NIST Team Aims to Develop Graphene Nanopore Sequencing Tech Premium Dec 15, 2015 Researchers Assess Variant Calling Pipelines Using Genome in a Bottle 'Gold Standard' Premium Aug 7, 2015 10X Genomics Provides First Look at Data From NIST Reference Samples Premium May 15, 2015 NIST, Genome in a Bottle Release First Reference Material for Assessing Genome Sequencing Feb 25, 2014 DDC Medical, NIST Ink Deal to Commercialize Mouse Cell Line Authentication Load More Breaking News SEC Concludes CareDx Investigation, Recommends No Enforcement Action Streck Quality Controls for DiaSorin's Luminex Sepsis Tests Receive FDA Clearance Adela Closes $48M Financing to Develop Cancer Monitoring, Early Detection Test 3EO Health At-Home Molecular COVID-19 Test Nabs FDA EUA Top Five Articles on GenomeWeb Last Week: IVDR Rollout, AI in Genomics, 10x vs. NanoString, More The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.