The technique provides the scientific community with a higher-resolution methodology to determine if a mouse cell line has been correctly identified in research.

The public-private consortium, led by the National Institute of Standards and Technology, recently released four new reference materials.

The material has a similar benefit to graphene, in that it is one-atom thin, but has the benefit that DNA does not stick to it as it translocates through the pore. 

The firm will provide DNA from at least 50 mouse cell lines for use in a PCR-based validation assay.

The partners have signed a three-year R&D agreement under which SeraCare will provide its ctDNA reference materials to NIST for comparison between labs.

The researchers found that many clinically relevant genes fall in regions of the genome that cannot be confidently sequenced and analyzed. 

Dozens of government agencies, academic institutions, and a various public and private sector organizations have now committed to driving the initiative forward.

The researchers propose attaching nucleobases to graphene nanopores in order to use the electrical and strain properties of graphene to read DNA.

Researchers tested a combination of three aligners and four variant callers on reference datasets, finding that each has its own biases. 

The firm discussed its technology, the NIST data, and data from some early customers in a webinar it hosted this week.


Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.