NICE Breast Cancer Molecular Tests Included in Recommendations by UK's NICE The group recommends Myriad Genetics' EndoPredict, NanoString's Prosigna, and Genomic Health's Oncotype DX tests for guiding chemotherapy decisions if certain conditions are met. UK's NICE Finalizing Updated Breast Cancer Test Guidance Following Stakeholder Comments Premium Although a draft guidance last month recommended against use of molecular tests to guide chemotherapy, the group's finalized decision is subject to price negotiation and other adjustments. NICE Draft Guidance Reverses Endorsement of Oncotype Dx to Guide Chemotherapy An assessment concluded that Oncotype Dx has not demonstrated a significant enough impact on outcomes or cost effectiveness compared to current practice. UK's NHS Adopts NICE Advice to Provide Oncotype DX for Intermediate Risk Breast Cancer Patients The NICE recommendation specifies the use of Oncotype DX for intermediate risk patients for whom doctors are unclear whether to prescribe chemotherapy. NHS Cancer Drug Fund Reevaluating Whether to Keep Providing Several Pricey Personalized Therapies Premium In order to keep the therapies in the fund, drugmakers will have to meet a cost and clinical efficacy threshold. NHS will also offer companies the chance to provide their treatments at a discount to meet the cost threshold. Feb 25, 2013 Most Viewed Articles on GWDN Last Week: Feb 25, 2013 Feb 20, 2013 In Preliminary Recommendation, UK's NICE Backs Oncotype DX in Subset of Breast Cancer Patients Premium Jan 23, 2013 UK's NICE Seeks Comments on Updated Guidelines for Familial Breast Cancer Genetic Testing, Treatment Premium Nov 2, 2012 UK Study Suggests VEGF Splice Isoform Ratio Could Predict Colorectal Cancer Patients' Avastin Response Premium Sep 12, 2012 During Investor Day, Roche Highlights Personalized Medicine as Key Area for Future Growth Premium May 2, 2012 Merck Serono Survey Finds Limited Test Access, High Costs a Barrier to Personalized Rx Adoption in UK Premium Feb 22, 2012 Lab21 Offering Companion Testing to Personalize ALK Inhibitors for NSCLC Patients Premium Feb 8, 2012 Breast Cancer Test Makers Will Attempt to Sway UK's NICE in Wake of Initial Negative Opinion Premium Oct 19, 2011 UK's NICE Cites Lack of Response Markers for BMS' Yervoy as Factor in Negative Recommendation Premium Jun 8, 2011 Q&A: NICE's Nick Crabb on Assessing Drugs and Diagnostics for the UK Medical System Premium Feb 23, 2011 NICE Agrees With FDA in Pulling Avastin's Indication for Metastatic Breast Cancer Premium Feb 16, 2011 Cancer Research UK on Path to Building National Genetic Testing Service Premium Aug 25, 2010 Despite PGx Leads, Avastin Access Debate Not Focused on Personalized Medicine Strategies Premium Jun 2, 2010 UK's NICE Backs Iressa Coverage at Fixed Price; NHS Pays for Genetic Testing Premium Apr 28, 2010 Resuscitation Uncertain: Can Debiopharm Help Revive Pfizer's Failed Melanoma Drug? Premium Apr 21, 2010 With New Hires to Pharma Business Development Team, Qiagen Prioritizes Rx/Dx Partnership Strategy Premium Apr 7, 2010 AstraZeneca Paying for Genetic Testing Services for UK Lung Cancer Patients Receiving Iressa Premium Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.