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NICE

UK's NICE Recommends Genetic Testing for Therapy Selection in Stroke Patients

Clopidogrel is less effective at preventing subsequent strokes in patients with certain variations in the CYP2C19 gene and testing could aid treatment selection.

NICE Recommends Genedrive Test in Draft Guidance to Prevent Hearing Loss in Newborns

NICE recommended that Genedrive's MT-RNR1 ID Kit should be adopted by the NHS for the prevention of antibiotic-induced hearing loss.

UK's NICE to Accelerate Assessment of Genedrive Test

NICE plans to assess Genedrive's MT-RNR1 test for antibiotics-induced hearing loss in infants via a new program.

Breast Cancer Molecular Tests Included in Recommendations by UK's NICE

The group recommends Myriad Genetics' EndoPredict, NanoString's Prosigna, and Genomic Health's Oncotype DX tests for guiding chemotherapy decisions if certain conditions are met.

UK's NICE Finalizing Updated Breast Cancer Test Guidance Following Stakeholder Comments
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Although a draft guidance last month recommended against use of molecular tests to guide chemotherapy, the group's finalized decision is subject to price negotiation and other adjustments.

Jan 10, 2018

NICE Draft Guidance Reverses Endorsement of Oncotype Dx to Guide Chemotherapy

Feb 5, 2015

UK's NHS Adopts NICE Advice to Provide Oncotype DX for Intermediate Risk Breast Cancer Patients

Nov 20, 2014

NHS Cancer Drug Fund Reevaluating Whether to Keep Providing Several Pricey Personalized Therapies
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Feb 25, 2013

Most Viewed Articles on GWDN Last Week: Feb 25, 2013

Feb 20, 2013

In Preliminary Recommendation, UK's NICE Backs Oncotype DX in Subset of Breast Cancer Patients
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Jan 23, 2013

UK's NICE Seeks Comments on Updated Guidelines for Familial Breast Cancer Genetic Testing, Treatment
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Nov 2, 2012

UK Study Suggests VEGF Splice Isoform Ratio Could Predict Colorectal Cancer Patients' Avastin Response
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Sep 12, 2012

During Investor Day, Roche Highlights Personalized Medicine as Key Area for Future Growth
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May 2, 2012

Merck Serono Survey Finds Limited Test Access, High Costs a Barrier to Personalized Rx Adoption in UK
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Feb 22, 2012

Lab21 Offering Companion Testing to Personalize ALK Inhibitors for NSCLC Patients
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Feb 8, 2012

Breast Cancer Test Makers Will Attempt to Sway UK's NICE in Wake of Initial Negative Opinion
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Oct 19, 2011

UK's NICE Cites Lack of Response Markers for BMS' Yervoy as Factor in Negative Recommendation
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Jun 8, 2011

Q&A: NICE's Nick Crabb on Assessing Drugs and Diagnostics for the UK Medical System
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Feb 23, 2011

NICE Agrees With FDA in Pulling Avastin's Indication for Metastatic Breast Cancer
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Feb 16, 2011

Cancer Research UK on Path to Building National Genetic Testing Service
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Aug 25, 2010

Despite PGx Leads, Avastin Access Debate Not Focused on Personalized Medicine Strategies
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Jun 2, 2010

UK's NICE Backs Iressa Coverage at Fixed Price; NHS Pays for Genetic Testing
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Apr 28, 2010

Resuscitation Uncertain: Can Debiopharm Help Revive Pfizer's Failed Melanoma Drug?
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Apr 21, 2010

With New Hires to Pharma Business Development Team, Qiagen Prioritizes Rx/Dx Partnership Strategy
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Apr 7, 2010

AstraZeneca Paying for Genetic Testing Services for UK Lung Cancer Patients Receiving Iressa
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Breaking News
The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.