NIAID

A new analysis finds that better grant-writing skills may help early-career researchers stay funded and stay in academia.

The company said it will use the funding to accelerate the development of an affordable sequencing test for metagenomic samples.

The new centers will generate genomic resources and tools for infectious disease research.

This Week in PLOS

In PLOS this week: hierarchical fine-mapping approach, genomic and sub-genomic variations in lab porcine epidemic diarrhea virus strains, and more.

First Stages

Early trial of experimental gene-based Zika vaccine indicates it is tolerated and leads to an antibody response.

The grant is specifically intended to support the development of noninvasive, rapid tests that can be used at the point of care in developing country settings.

An exome sequencing analysis of individuals from eight families led to homozygous loss-of-function mutations in CD55 and ties to complement system activity.

After identifying mutations in CARD11 in individuals with severe atopic dermatitis, investigators began untangling potential signaling consequences.

A US National Institute of Allergy and Infectious Diseases-led team sequenced the exome of a young girl with recurrent, severe infections to uncover the gene variant.

NIH researchers got tantalizingly close to long-term engraftment at levels that could provide a clinical benefit in gene therapy applications.

Pages

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.