NIAID

The new centers will generate genomic resources and tools for infectious disease research.

This Week in PLOS

In PLOS this week: hierarchical fine-mapping approach, genomic and sub-genomic variations in lab porcine epidemic diarrhea virus strains, and more.

First Stages

Early trial of experimental gene-based Zika vaccine indicates it is tolerated and leads to an antibody response.

The grant is specifically intended to support the development of noninvasive, rapid tests that can be used at the point of care in developing country settings.

An exome sequencing analysis of individuals from eight families led to homozygous loss-of-function mutations in CD55 and ties to complement system activity.

After identifying mutations in CARD11 in individuals with severe atopic dermatitis, investigators began untangling potential signaling consequences.

A US National Institute of Allergy and Infectious Diseases-led team sequenced the exome of a young girl with recurrent, severe infections to uncover the gene variant.

NIH researchers got tantalizingly close to long-term engraftment at levels that could provide a clinical benefit in gene therapy applications.

Make Your Own Vaccine

There are a number of efforts underway to develop DNA vaccines for diseases like Zika, according to the Wall Street Journal.

The agency has committed $11 million for the creation of a network of research centers that will use systems biology approaches to build predictive models for infectious diseases.

Pages

Oxford Nanopore Technologies is looking into dual listings in London and Hong Kong, according to the South China Morning Post.

The New York Times looks into medical research funding in the US and how the grant system might not be funding the best work.

US lawmakers proposed increasing the National Science Foundation budget, including its facilities account, Science reports.

In PNAS this week: effects of gene deletions on bacterial metabolic networks, genetic responses to sea star wasting disease, and more.