The UPenn team will collect genetic information from outside patient cohorts, reorganize it in a streamlined process, and provide a database for downstream studies.
Both a genome-wide association study and a rare variant burden analysis homed in on a role for KIF5A mutations in amyotrophic lateral sclerosis.
A meta-analysis based on genotyping data for more than 400,000 people with or without the disease led to 17 new risk loci mined for candidate genes
The initiative was launched to conduct a large-scale study of cognitive impairment and Alzheimer's disease to advance the discovery of biomarkers of the conditions.
UPenn will establish the Coordinating Center for Genetics and Genomics of Alzheimer's Disease in collaboration with five other institutions.
The agency will soon accept applications from institutions interested in assuming responsibility for its Genetics of Alzheimer's Disease Data Storage Site.
The agency said that it will provide up to five years of funding to one institute to run the National Cell Repository for Alzheimer's Disease.
The award will support a collection of biosamples used in aging research and housed at the institute.
The National Institutes of Health plans to fund a coordination center to facilitate the replication phase of the Alzheimer's Disease Sequencing Project.
NEW YORK (GenomeWeb) – The National Institute on Aging plans to award up to $800,000 next year to investigators' efforts to develop and plan research projects that will examine epigenetic factors involved in age-related diseases, NIA said Friday.
A genomic analysis of modern and ancient maize reveals a complicated domestication history, according to Reuters.
In PLOS this week: MYRF variant linked to congenital diaphragmatic hernia, analysis of the "dragon's blood" red resin produced by traditional medicine plants, and more.
CNBC reports that half of academic researchers leave after about five years.
Researchers have used genetic analysis to confirm a new type of salamander, the New York Times reports.