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NHLBI

CardioVar Consortium Wins $8.2M From NHLBI to Map Heart Disease Variants, Functional Effects

The investigators hope to eventually create a decision support resource with utility for physicians evaluating genetic test results in heart disease patients.

TOPMed Researchers Offer Guidance for Use of Race, Ethnicity, Ancestry Data in Genomic Research

While originally developed for the TOPMed program, the authors said the recommendations could be widely applicable to genetic research in diverse populations.

New Leukocyte-Linked Loci Uncovered With Multi-Ancestry Genomes

Using genome sequence data for more than 61,800 diverse TOPMed participants, researchers found seven new loci with significant ties to leukocyte traits.

Analysis of TOPMed Genomes Finds Many Previously Undescribed Variants

In the first 53,831 samples, the researchers detected more than 410 million variants. almost 80 percent of which had not been described before.

Heart Transplant Cell-Free DNA Test Enables Earlier Detection of Acute Rejection Than Biopsy
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The researchers hope that donor-derived cell-free DNA testing to monitor rejection can help relieve racial disparities in heart transplant outcomes.

Nov 26, 2019

Geisinger Awarded $2.8M Grant for Familial Hypercholesterolemia Research

Jan 24, 2019

Liquid Biopsy Dx Looks for Donor-Derived DNA as Measure of Chronic Lung Transplant Rejection
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Sep 26, 2018

Single-Cell Analysis Elucidates Features of Nucleosome Organization

Nov 6, 2017

NIH Awards $9M in Funding to Support Data Commons Pilot Phase

Apr 14, 2017

NIH Commits $12M to Fund Omics Data Analysis Projects

Apr 6, 2017

New Studies Demonstrate Utility of iPSC Technology for Genetic Research

Sep 14, 2016

NIH, Sellas Life Sciences to Collaborate on AML Diagnostic

Apr 19, 2016

Precision Medicine Program to Get $9.3M in NHLBI Funding for Omics Research

Jan 5, 2016

Cincinnati Children's Awarded $5.7M NIH Grant to Manage Pediatric Cardiovascular Disease Consortia

Oct 29, 2015

NY Genome Center Wins $13.5M from NHLBI Precision Medicine Program

Oct 8, 2015

Broad Nabs $40M From NHLBI for Large-Scale Whole-Genome Sequencing Project

Oct 2, 2015

UCSF Team Using NHLBI Grant to ID Lung Disease Protein Markers in Premature Infants
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Jun 24, 2015

WiCell to Distribute Human Stem Cell Lines from NHLBI Studies

Apr 16, 2015

NHLBI-led Team Untangles Gene Networks Involved in Blood Pressure Regulation

Feb 19, 2015

MCW Awarded $8M to Fund Rat Genome Database

Nov 5, 2014

NHLBI Awards $7.3M Contract to Moffitt, M2Gen to Coordinate Lab, Biorepository for MDS Study

Sep 19, 2014

Cofactor Genomics Wins $300K Contract for Epigenetics Study of Cardiovascular Disease

Sep 17, 2014

Large-scale Sequencing Studies ID Variants Associated with Lower Lipid Levels, Less Heart Disease
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Jul 9, 2014

NIH to Fund New Pediatric Cardiac Genomics Centers

Mar 26, 2014

ABRF Panelists Discuss NIH Efforts for Sharing Big Data

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The Scan

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.

SpliceVault Portal Provides Look at RNA Splicing Changes Linked to Genetic Variants

The portal, described in Nature Genetics, houses variant-related messenger RNA splicing insights drawn from RNA sequencing data in nearly 335,700 samples — a set known as the 300K-RNA resource.

Automated Sequencing Pipeline Appears to Allow Rapid SARS-CoV-2 Lineage Detection in Nevada Study

Researchers in the Journal of Molecular Diagnostics describe and assess a Clear Labs Dx automated workflow, sequencing, and bioinformatic analysis method for quickly identifying SARS-CoV-2 lineages.

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.