NHLBI Blood-Based MRD Testing Identifies AML Patients at Risk of Relapse After Stem Cell Transplant Researchers looked at AML variants in the blood of patients prior to their allogeneic hematopoietic cell transplant and correlated them with subsequent relapse or death. CardioVar Consortium Wins $8.2M From NHLBI to Map Heart Disease Variants, Functional Effects The investigators hope to eventually create a decision support resource with utility for physicians evaluating genetic test results in heart disease patients. TOPMed Researchers Offer Guidance for Use of Race, Ethnicity, Ancestry Data in Genomic Research While originally developed for the TOPMed program, the authors said the recommendations could be widely applicable to genetic research in diverse populations. New Leukocyte-Linked Loci Uncovered With Multi-Ancestry Genomes Using genome sequence data for more than 61,800 diverse TOPMed participants, researchers found seven new loci with significant ties to leukocyte traits. Analysis of TOPMed Genomes Finds Many Previously Undescribed Variants In the first 53,831 samples, the researchers detected more than 410 million variants. almost 80 percent of which had not been described before. Jan 27, 2021 Heart Transplant Cell-Free DNA Test Enables Earlier Detection of Acute Rejection Than Biopsy Premium Nov 26, 2019 Geisinger Awarded $2.8M Grant for Familial Hypercholesterolemia Research Jan 24, 2019 Liquid Biopsy Dx Looks for Donor-Derived DNA as Measure of Chronic Lung Transplant Rejection Premium Sep 26, 2018 Single-Cell Analysis Elucidates Features of Nucleosome Organization Nov 6, 2017 NIH Awards $9M in Funding to Support Data Commons Pilot Phase Apr 14, 2017 NIH Commits $12M to Fund Omics Data Analysis Projects Apr 6, 2017 New Studies Demonstrate Utility of iPSC Technology for Genetic Research Sep 14, 2016 NIH, Sellas Life Sciences to Collaborate on AML Diagnostic Apr 19, 2016 Precision Medicine Program to Get $9.3M in NHLBI Funding for Omics Research Jan 5, 2016 Cincinnati Children's Awarded $5.7M NIH Grant to Manage Pediatric Cardiovascular Disease Consortia Oct 29, 2015 NY Genome Center Wins $13.5M from NHLBI Precision Medicine Program Oct 8, 2015 Broad Nabs $40M From NHLBI for Large-Scale Whole-Genome Sequencing Project Oct 2, 2015 UCSF Team Using NHLBI Grant to ID Lung Disease Protein Markers in Premature Infants Premium Jun 24, 2015 WiCell to Distribute Human Stem Cell Lines from NHLBI Studies Apr 16, 2015 NHLBI-led Team Untangles Gene Networks Involved in Blood Pressure Regulation Feb 19, 2015 MCW Awarded $8M to Fund Rat Genome Database Nov 5, 2014 NHLBI Awards $7.3M Contract to Moffitt, M2Gen to Coordinate Lab, Biorepository for MDS Study Sep 19, 2014 Cofactor Genomics Wins $300K Contract for Epigenetics Study of Cardiovascular Disease Sep 17, 2014 Large-scale Sequencing Studies ID Variants Associated with Lower Lipid Levels, Less Heart Disease Premium Jul 9, 2014 NIH to Fund New Pediatric Cardiac Genomics Centers Load More Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.