NHLBI Analysis of TOPMed Genomes Finds Many Previously Undescribed Variants In the first 53,831 samples, the researchers detected more than 410 million variants. almost 80 percent of which had not been described before. Heart Transplant Cell-Free DNA Test Enables Earlier Detection of Acute Rejection Than Biopsy Premium The researchers hope that donor-derived cell-free DNA testing to monitor rejection can help relieve racial disparities in heart transplant outcomes. Geisinger Awarded $2.8M Grant for Familial Hypercholesterolemia Research Geisinger researchers will work with collaborators at the nonprofit FH Foundation to develop new methods for the identification and cascade testing of FH. Liquid Biopsy Dx Looks for Donor-Derived DNA as Measure of Chronic Lung Transplant Rejection Premium A team led by researchers at the NHLBI are testing the efficacy of measuring ddcfDNA in blood as a biomarker of chronic rejection for lung transplants. Single-Cell Analysis Elucidates Features of Nucleosome Organization Nucleosome organization appears to follow two principles, according to the researchers' analyses of three different cell types. Nov 6, 2017 NIH Awards $9M in Funding to Support Data Commons Pilot Phase Apr 14, 2017 NIH Commits $12M to Fund Omics Data Analysis Projects Apr 6, 2017 New Studies Demonstrate Utility of iPSC Technology for Genetic Research Sep 14, 2016 NIH, Sellas Life Sciences to Collaborate on AML Diagnostic Apr 19, 2016 Precision Medicine Program to Get $9.3M in NHLBI Funding for Omics Research Jan 5, 2016 Cincinnati Children's Awarded $5.7M NIH Grant to Manage Pediatric Cardiovascular Disease Consortia Oct 29, 2015 NY Genome Center Wins $13.5M from NHLBI Precision Medicine Program Oct 8, 2015 Broad Nabs $40M From NHLBI for Large-Scale Whole-Genome Sequencing Project Oct 2, 2015 UCSF Team Using NHLBI Grant to ID Lung Disease Protein Markers in Premature Infants Premium Jun 24, 2015 WiCell to Distribute Human Stem Cell Lines from NHLBI Studies Apr 16, 2015 NHLBI-led Team Untangles Gene Networks Involved in Blood Pressure Regulation Feb 19, 2015 MCW Awarded $8M to Fund Rat Genome Database Nov 5, 2014 NHLBI Awards $7.3M Contract to Moffitt, M2Gen to Coordinate Lab, Biorepository for MDS Study Sep 19, 2014 Cofactor Genomics Wins $300K Contract for Epigenetics Study of Cardiovascular Disease Sep 17, 2014 Large-scale Sequencing Studies ID Variants Associated with Lower Lipid Levels, Less Heart Disease Premium Jul 9, 2014 NIH to Fund New Pediatric Cardiac Genomics Centers Mar 26, 2014 ABRF Panelists Discuss NIH Efforts for Sharing Big Data Feb 26, 2014 NHLBI Awards Medical College of Wisconsin $1.5M for Kidney Failure Research Feb 12, 2014 New Trial to Study Asthma Drug Responses, Genetic Factors in African-Americans Feb 11, 2014 MCW Lab Lands $8.7M to Create Knockout Rats for Modeling Disease Genetics Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.