Nucleosome organization appears to follow two principles, according to the researchers' analyses of three different cell types.
Participants in the pilot will begin developing the capabilities required for the planned data commons, including making data transparent and interoperable.
The funding will support research projects using data from the Trans Omics for Precision Medicine program to uncover disease pathology.
Eleven new studies from the NHLBI NextGen Consortium show different uses for iPSCs to study polygenetic diseases across various systems in the human body.
The partners are developing an assay to detect minimal residual disease in leukemia patients, for use with Sellas' investigational AML drug.
Funded projects will support the agency's Trans Omics for Precision Medicine program, which is focused on heart, lung, blood, and sleep disorders.
The CCHMC will act as the coordinating center for members of the NHLBI's Cardiovascular Development Consortium and Pediatric Cardiac Genomics Consortium.
The center has already sequenced and analyzed 1,500 human genomes for the TOPMed program and will expand this effort with the new funding.
The funding will support the Broad's sequencing of 20,000 individuals as part of the NHLBI's Trans-Omic for Precision Medicine program.
The group hopes to find biomarkers as a first step toward identifying or developing targeted therapeutics to avoid serious and life threatening outcomes of early lung disease in these newborns.
Customers might want to consider what they might learn about their risk of diseases like Alzheimer's before snagging the genetic testing kits that are on many gift guides this year, NJ.com writes.
The Wall Street Journal reports there is uncertainty surrounding whether He Jiankui's embryo editing did what he said it did.
Stat News reports that the pause on procuring fetal tissue for intramural US National Institutes of Health research will soon affect additional labs there.
In Nature this week: genomic analysis of the invasive fall webworm, amp of constrained coding regions within the human genome, and more.