Newcastle University De Novo Mutations Linked to Male Infertility in Trio Exome Sequencing Study At the ASHG annual meeting this week, a Newcastle University researcher described efforts to find de novo mutations behind oligozoospermia or azoospermia. Blood, Immune Cell Formation in Fetal Bone Marrow Detailed in Cell Atlas Effort The researchers found that blood and immune cells quickly diversify within fetal bone marrow, but that there are differences in Down syndrome samples. Skin Cell Atlas Elucidates Pathological Cell States Underlying Inflammatory Skin Diseases Researchers profiled the transcriptomes of more than 500,000 single cells from human fetal skin and adult skin with atopic dermatitis and psoriasis. Nonalcoholic Fatty Liver Disease Progression Can Be Traced by Gene Expression Signature A transcriptomic study found 25 genes that are differentially expressed at various disease stages, suggesting the proteins they encode could serve as biomarkers. Human Kidney Immune Cell Map Reveals Multiple Infection Protection Zones Researchers from Wellcome Sanger Institute and elsewhere found that the immune landscape of the kidney is zoned to counter dominant immunological challenges. Sep 20, 2018 European Cancer Charities Award $39.4M in Research Grants Aug 9, 2018 Single-Cell Transcriptome Atlas Elucidates Features Shared by Cancerous, Normal Kidneys Jun 5, 2017 With Moon Software Launch, Diploid Aims to Accelerate Diagnosis of Rare Genetic Diseases Premium Mar 24, 2014 Chromothripsis Event Touches off Development of Rare Form of Acute Lymphoblastic Leukemia Jan 24, 2013 Europe Pumps $50M into Genome-based International Rare Disease Projects Nov 29, 2012 DNA2.0, Newcastle University Partner to Develop Expression System for B. Subtillis May 24, 2012 UK Agency Granting $7.9M to Develop Synthetic Bio Technology Platform Feb 2, 2011 MDxHealth Nets Methylation Biomarker Deal with Pfizer, Partners for PARP Inhibitor Premium Feb 2, 2011 iSAEC Using HMO Research Network's EMRs to Recruit Patients for PGx Studies Premium Sep 30, 2010 SAEC Names New Partners, Launches Stage II Sep 9, 2010 SAEC Partners with Liverpool, Newcastle Universities on PGx Aug 12, 2009 Horizon Racks Up More Academic Research, Licensing Deals with Torino, Newcastle Universities Premium Aug 11, 2009 Newcastle University to Use Horizon's X-MAN Models Feb 19, 2009 Genetics Improves Some Warfarin Dosing; Clinical Trials Next Breaking News Delic Partners With GT Research for Genetic Analysis of Cannabis, Psychedelic Mushrooms Indivumed, Biognosys Expand Partnership to Offer Immunopeptidomics Insights Multiomic Study Identifies Drivers of Severe COVID-19 in Patients Under 50 Without Comorbidities Yourgene H1 2022 Revenues More Than Double Gencove Raises $10M in Series A Financing Blueprint Genetics, BioMarin to Offer Genetic Testing for Skeletal Dysplasia in Europe, Middle East The Scan Should've Been Spotted Sooner Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier. For Martian Fuel Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo. To Boost Rapid Testing The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests. PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.