Netherlands Cancer Institute Single Metastatic Cancer Genome Analysis Appears Sufficient to ID Biomarkers, Treatment Options For many metastatic cancer patients, actionable genomic alterations uncovered in the initial analysis did not change much in later biopsies. With Support From Lawmakers, WGS Becoming More Accessible to Netherlands' Cancer Patients Premium Based on results from a pilot study, Dutch lawmakers are advancing a proposal to make WGS a standard test for advanced cancer patients. Breast Cancer Polygenic Risk Score Can Help Predict Risk of Contralateral Disease Based on the study results, the score could be combined with other risk factors to improve predictions of contralateral breast cancer and stratify patients. Metastatic Cancer Treatment Markers Identified in Clinical WGS Study Interim results from a study in the Netherlands suggest whole-genome sequencing can be done fast enough to uncover treatment targets in metastatic cancer patients. Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds. Sep 30, 2019 Netherlands Drug Repurposing, Tumor Profiling Trial Results Reported at ESMO Jul 24, 2019 Dutch Startup Gen-X Offers Functional Genome Annotation Services Premium Jan 15, 2018 Desktop Genetics Licenses Genome Editing Assessment Tech Feb 10, 2017 Cancer Research UK Unveils First Winners of Grand Challenge Competition Jul 14, 2016 Immune Gene Mutations Found in Immunotherapy-Resistant Metastatic Melanoma Patients May 10, 2016 'Immunogram' Could Better Personalize Cancer Immunotherapy, Researchers Say Premium Aug 3, 2012 Dutch Researchers Head SU2C Tumor Profiling Study Mar 9, 2012 Netherlands Provides $18M for New Proteomics Facility Oct 31, 2011 EU Funds Breast Cancer Profiling Consortium Jun 15, 2011 Agendia to Collaborate with MD Anderson, Netherlands Institute to Further Validate ColoPrint Premium Jun 9, 2011 Agendia, MD Anderson, Netherlands Cancer Institute Partner on Colorectal Cancer Research May 10, 2011 Agendia, AstraZeneca, NKI Partner to ID Colorectal Cancer Subtypes Breaking News Imaging Mass Cytometry Discovers Tumor Microenvironment Features Predicting Lung Cancer Outcomes Metastatic Tumor Subtypes Found With Expression Profiling GenomeWeb Top 40 up 4 Percent in January, Following Broader Upswing LumiraDx Receives Notice From Nasdaq Over Missed Listing Requirement Sherlock Biosciences to Acquire Sense Biodetection The Scan Study Links Evolution of Longevity, Social Organization in Mammals With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals. Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival. CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system. Drug Response Variants May Be Distinct in Somatic, Germline Samples Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.