Netherlands Cancer Institute

The technology quantifies the efficacy of genome-editing methods and identifies the predominant types of insertions and deletions in a targeted pool of cells.

The competition was established in 2015 to fund studies addressing the biggest challenges in cancer research.

Using exome sequencing, researchers unearthed apparent anti-PD-1 resistance mutations in three of four individuals treated for metastatic melanoma.

The seven-parameter proposal potentially offers a way to assess how the immune system and a cancer interact on a broader level in order to better guide treatment.

NEW YORK (GenomeWeb News) – A group of Dutch-led research partners will use a €1.2 million ($1.5 million) grant awarded under a collaboration with Stand Up 2 Cancer (SU2C) to fund a genomics-based project seeking to use tumor profiles to predict patient response to cancer treatments.

"We will use multiple 'omics' technologies to ask which kinase signaling pathways are activated in colon cancer," an Agendia spokesperson said of the collaboration, which will also provide independent validation of the company's ColoPrint colon cancer recurrence test.

The partners will use an integrated approach combining genomics and proteomics to better understand colorectal cancer biology.

The partners will seek to identify specific colorectal cancer subtypes in order to develop targeted therapies.

Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.