Netherlands Cancer Institute
Single Metastatic Cancer Genome Analysis Appears Sufficient to ID Biomarkers, Treatment Options
For many metastatic cancer patients, actionable genomic alterations uncovered in the initial analysis did not change much in later biopsies.
Based on results from a pilot study, Dutch lawmakers are advancing a proposal to make WGS a standard test for advanced cancer patients.
Breast Cancer Polygenic Risk Score Can Help Predict Risk of Contralateral Disease
Based on the study results, the score could be combined with other risk factors to improve predictions of contralateral breast cancer and stratify patients.
Metastatic Cancer Treatment Markers Identified in Clinical WGS Study
Interim results from a study in the Netherlands suggest whole-genome sequencing can be done fast enough to uncover treatment targets in metastatic cancer patients.
Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift
Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds.