Netherlands Cancer Institute | GenomeWeb

Netherlands Cancer Institute

Using exome sequencing, researchers unearthed apparent anti-PD-1 resistance mutations in three of four individuals treated for metastatic melanoma.

The seven-parameter proposal potentially offers a way to assess how the immune system and a cancer interact on a broader level in order to better guide treatment.

NEW YORK (GenomeWeb News) – A group of Dutch-led research partners will use a €1.2 million ($1.5 million) grant awarded under a collaboration with Stand Up 2 Cancer (SU2C) to fund a genomics-based project seeking to use tumor profiles to predict patient response to cancer treatments.

"We will use multiple 'omics' technologies to ask which kinase signaling pathways are activated in colon cancer," an Agendia spokesperson said of the collaboration, which will also provide independent validation of the company's ColoPrint colon cancer recurrence test.

The partners will use an integrated approach combining genomics and proteomics to better understand colorectal cancer biology.

The partners will seek to identify specific colorectal cancer subtypes in order to develop targeted therapies.

In Science this week: genetic analysis of pollutant-tolerant fish, and more.

Researchers have found a rare carbapenem resistance gene on a US pig farm, NBC News reports.

New York officials are considering the use of a familial DNA search to get a lead on a suspect in the strangulation death of a runner.

NIH Director Francis Collins has selected a retired Army major general and cardiologist for the CEO spot at the agency's embattled Clinical Center.