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Netherlands Cancer Institute

Single Metastatic Cancer Genome Analysis Appears Sufficient to ID Biomarkers, Treatment Options

For many metastatic cancer patients, actionable genomic alterations uncovered in the initial analysis did not change much in later biopsies.

With Support From Lawmakers, WGS Becoming More Accessible to Netherlands' Cancer Patients
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Based on results from a pilot study, Dutch lawmakers are advancing a proposal to make WGS a standard test for advanced cancer patients.

Breast Cancer Polygenic Risk Score Can Help Predict Risk of Contralateral Disease

Based on the study results, the score could be combined with other risk factors to improve predictions of contralateral breast cancer and stratify patients.

Metastatic Cancer Treatment Markers Identified in Clinical WGS Study

Interim results from a study in the Netherlands suggest whole-genome sequencing can be done fast enough to uncover treatment targets in metastatic cancer patients.

Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift

Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds.

Sep 30, 2019

Netherlands Drug Repurposing, Tumor Profiling Trial Results Reported at ESMO

Jul 24, 2019

Dutch Startup Gen-X Offers Functional Genome Annotation Services
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Jan 15, 2018

Desktop Genetics Licenses Genome Editing Assessment Tech

Feb 10, 2017

Cancer​ ​Research​ ​UK​ ​Unveils​ ​First​ ​Winners​ ​of​ ​Grand​ ​Challenge​ ​Competition

Jul 14, 2016

Immune Gene Mutations Found in Immunotherapy-Resistant Metastatic Melanoma Patients

May 10, 2016

'Immunogram' Could Better Personalize Cancer Immunotherapy, Researchers Say
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Aug 3, 2012

Dutch Researchers Head SU2C Tumor Profiling Study

Mar 9, 2012

Netherlands Provides $18M for New Proteomics Facility

Oct 31, 2011

EU Funds Breast Cancer Profiling Consortium

Jun 15, 2011

Agendia to Collaborate with MD Anderson, Netherlands Institute to Further Validate ColoPrint
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Jun 9, 2011

Agendia, MD Anderson, Netherlands Cancer Institute Partner on Colorectal Cancer Research

May 10, 2011

Agendia, AstraZeneca, NKI Partner to ID Colorectal Cancer Subtypes

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The Scan

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.

Tumor Microenvironment Immune Score Provides Immunotherapy Response, Prognostic Insights

Using multiple in situ analyses and RNA sequence data, researchers in eBioMedicine have developed a score associated with immunotherapy response or survival.

CRISPR-Based Method for Finding Cancer-Associated Exosomal MicroRNAs in Blood

A team from China presents in ACS Sensors a liposome-mediated membrane fusion strategy for detecting miRNAs carried in exosomes in the blood with a CRISPR-mediated reporter system.

Drug Response Variants May Be Distinct in Somatic, Germline Samples

Based on variants from across 21 drug response genes, researchers in The Pharmacogenomics Journal suspect that tumor-only DNA sequences may miss drug response clues found in the germline.