NCI NIH Awards $73M to Continue Buildout of ClinGen NHGRI and NCI are supplying the funds over five years to teams at five institutions that have been leading the ClinGen effort since its initial inception in 2013. Natera Signatera Test to be Used in Study of MRD-Guided Treatment for Colon Cancer Patients Patients will be randomized to receive various chemotherapy regimens depending on how Signatera identifies their minimal residual disease status. Lung Cancers in Non-Smokers Fall Into Informative Molecular Subtypes Whole-genome sequencing of lung cancers in never smokers highlighted three copy number-based subtypes, along with alterations linked to patient outcomes. Blood Testing Distinguishes Benign Tumors From Precancerous Condition Researchers used ultra-low-pass whole genome sequencing and cell-free DNA fragment size selection to detect pre-cancer in neurofibromatosis type 1 patients. NIH Earmarks $38M for Consortium Studying Polygenic Risk Scores in Diverse Populations The consortium aims to develop and evaluate methods for calculating polygenic risk scores for specific diseases, particularly for people of different ancestries. Jun 3, 2021 Crown Bioscience Licenses Cell Line Portfolio From NCI, ATCC Apr 29, 2021 Geisinger Health System Wins $3.6M NIH Grant to Study Genetics of Cancer Risk Apr 22, 2021 Genomic Effects of Radiation From Chernobyl Nuclear Disaster Examined in New Studies Apr 11, 2021 NCI Director Sharpless Outlines Ideas to Aggressively Lower Cancer Deaths Apr 7, 2021 NCI Launching Fourth Phase of CPTAC With Anticipated $56M in Funding Apr 2, 2021 New Approach May Help Predict Tissue-Specific Gene Expression From Whole Blood Transcriptomes Mar 24, 2021 NCI's Sharpless Calls Data Science 'Critical' to Cancer Research, Precision Oncology Premium Feb 17, 2021 NCI Grants $1.9M to Roswell Park to Study Molecular Race-Based Breast Cancer Disparities Jan 27, 2021 Small Cell Lung Cancer Study Uncovers Disease-Associated Germline Mutations Jan 5, 2021 Mutations in Mitochondrial DNA Underlie Certain Subtype of Aggressive Renal Cancer Dec 9, 2020 Nonprofit Friends of Cancer Research Launches Public-Private HRD Harmonization Project Nov 19, 2020 Exceptional Responders Cancer Study Points to Possible Treatment Targets Premium Oct 16, 2020 NIH Kicks Off Second Stage of 4D Nucleome Program With $142M in Research Grants Oct 14, 2020 NCI-MATCH Data Shows Value of Platform Trials for Patients With Rare Genomically Driven Cancers Premium Sep 18, 2020 NCI Awards InheRET $2M SBTT Grant to Improve Inherited Disease Detection Jul 24, 2020 TMB Harmonization Effort Yields Calibration Method to Correct Inter-Assay Variation Premium Apr 28, 2020 NCI Awards UCLA Researchers $2.8M to Develop Blood Test for Liver Transplant Candidate Selection Apr 27, 2020 Cutaneous Melanoma Clues Found From Risky SNPs, Related Traits Analyses Mar 19, 2020 Study Finds 28 Percent of Osteosarcoma Patients Have High-Penetrance Germline Mutations Feb 10, 2020 President Trump Calls for 8 Percent Cut to NIH Budget Load More Breaking News Beckman Coulter, Invitae Partner to Develop NGS Library Prep Applications Sick Infants Profiled with WGS See Better Diagnosis, More Care Changes UC Santa Cruz Center for Live Cell Genomics Wins $13.5M NIH Grant Genetron Health, Impact Therapeutics Partner for Anti-Cancer Drug, CDx Development Canaccord Genuity Initiates Coverage of Pacific Biosciences With Buy Rating Alternative Genetic Counseling Approach Leads to Higher Patient Satisfaction, Study Suggests The Scan Highly Similar Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News. Gain of Oversight According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research. Lasker for mRNA Vaccine Work The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.