NCI

NASA's Jet Propulsion Laboratory is providing informatics services for an NCI-funded project to standardize cancer genomics ontologies.

The five-year award will provide funding for researchers to investigate genetic determinants of Barrett's Esophagus and esophageal adenocarcinoma.

Sharpless for NCI

President Donald Trump is to name the University of North Carolina-Chapel Hill's Norman Sharpless as director of the National Cancer Institute.

The companies will perform tumor profiling to identify patients with genetic abnormalities that could make them eligible for treatment in the NCI study.

The agency hopes to gain data on the efficacy of BRAF targeted drugs used in sequence, and how physicians implement treatments compared to how the drugs are labelled.

The institute will join the NCI's Cancer Systems Biology Consortium, which is studying cancer initiation, progression, and metastasis.

Analyses of T cell therapy-responsive metastatic HPV-positive cervical cancers suggest the immune cells largely respond to tumor rather than viral antigens.

The Genomic Data Commons, the MMRF, and the Project GENIE are all inking new arrangements around sharing genomics data and crowdsourcing analysis.  

The multi-center precision medicine trial has matched approximately 700 patients to 24 treatment arms so far, but some arms appear to be falling short of their recruitment goal.

Researcher Amanda Paulovich will develop multiple-reaction monitoring mass spectrometry assays and apply them to samples from cancer patients in the program.

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The partially reinstated US travel ban leaves space for uncertainty for researchers, Nature News says.

Researchers find a number of traits differ by sex and could affect mouse model studies, according to Reuters.

Tweaking the skin microbiome could help address some skin conditions, the New York Times reports.

In PNAS this week: DNA methylation profiles of tumor tissue, gene dynamics in prokaryotes, and more.