NCBI

David Lipman, who has led the US National Center for Biotechnology Information for decades, is stepping down.

The company submitted more than 95,000 recently re-curated variants identified in more than 1,500 genomes sequenced in Illumina's Clinical Services Laboratory.

Discovered and characterized through a collaboration between Feng Zhang's lab and the NCBI, C2c2 opens up the RNA world to editing and other applications.

Participants in the three-day hackathon, to be held early next year, will develop tools for analyzing NGS data in the context of specific research questions.

A study in Molecular Cell shows CRISPR-Cas9-like genome editing in human cells and suggests one protein could be an RNA-guided, RNA-cleaving endonuclease.

The National Center for Biotechnology Information is working on renaming incorrectly labeled genomes, according to Mike the Mad Biologist.

The Cas9 enzyme from S. aureus can be delivered by a viral vector and could lead to more CRISPR-based research tools and novel study designs in animal models.

The 100K Genome Project has added 20 newly completed genome sequences of foodborne pathogens generated using Pacific Biosciences' single-molecule sequencing technology to the National Center for Biotechnology Information's public database.

With this week's relaunch of the GeneTests website, formerly operated by the National Institutes of Health, Bio-Reference Laboratories chose to maintain very basic information about genetic tests, instead of asking for data t

Women with a family history of breast and ovarian cancer who are interested in getting genetically tested to gauge whether they have a heightened risk for the diseases should speak to a genetic counselor before getting tested, patient groups are advising their members.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.