At the AACR meeting, Elaine Mardis detailed efforts at Nationwide Children's Hospital to sequence patients' DNA and RNA to help inform therapeutic decisions.
The hospital is in the process of clinically validating a sequencing pipeline for its pediatric cancer patients, with the goal of demonstrating clinical utility.
A decade after their team at WashU sequenced the first tumor-normal genome pair, Mardis and Wilson are bringing cancer genomics to the clinic at Nationwide Children's Hospital.
With computing infrastructure in place, Nationwide Children's Hospital's Institute for Genomic Medicine is giving clinicians new tools for diagnosis and treatment.
Despite years of experience of returning genetic test results, clinicians and researchers are still faced with many questions, such as what to do about VUS and secondary findings.
The donation will support research at the Institute of Genomic Medicine, as well as research efforts in heart health, neonatology, and injury prevention.
The platform features a more comprehensive list of pipelines, simplifies data movement and flow, and reduces analysis times.
Richard Wilson and Elaine Mardis plan to use comprehensive sequencing to transition genomic discoveries into clinical assays for pediatric cancer and germline disorders.
The recruitment of Rick Wilson and Elaine Mardis from Washington University in St. Louis was made possible by a new $10 million gift from the Nationwide Foundation.
The team has been monitoring changes in host gene expression patterns due to different types of infections, and hopes to develop a diagnostic test.
The American Prospect writes that the pilot program to test the DNA of migrants could lead to more family separations.
An international commission is to develop a report on how researchers, clinicians, and regulators should evaluate the clinical applications of human germline genome editing.
The US Department of Agriculture presents a new blueprint for animal genomic research.
In Genome Research this week: repetitive element deletion linked to altered methylation and more in form of muscular dystrophy; human contamination in draft bacterial and archaeal genomes; and more.